42 products were found matching "K01201"!

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 40-536aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Target Protein Sequence: ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 40-536aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA LNILALSPPA QNLLLKSYFS EEGIGYNIIR...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 40-536aa. Protein Length: Full Length of Mature Protein. Tag Info: Tag-Free. Target Protein Sequence: ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA LNILALSPPA QNLLLKSYFS EEGIGYNIIR VPMASCDFSI...

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 20-515aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: AQPCIPKSFG YSSVVCVCNA SYCDSLDPVT LPALGTFSRY ESTRRGRRME LSVGAIQANR TGTGLLLTLQ PEKKFQKVKG FGGAMTDATA LNILALSPPT QKLLLRSYFS...

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 20-515aa. Protein Length: Full Length of Mature Protein. Tag Info: Tag-Free. Target Protein Sequence: AQPCIPKSFG YSSVVCVCNA SYCDSLDPVT LPALGTFSRY ESTRRGRRME LSVGAIQANR TGTGLLLTLQ PEKKFQKVKG FGGAMTDATA LNILALSPPT QKLLLRSYFS TNGIEYNIIR VPMASCDFSI...

Conduritol B epoxide (CBE) is an irreversible inhibitor of glucocerebrosidase, also known as acid beta-glucosidase, glucosylceramidase, GBA, or GBA1 (IC50 = 9 µM). Inhibition of this lysosomal glucosidase results in the accumulation of glucocerebroside without affecting cell viability, lysosomal enzyme release, or...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GbA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GbA. Next,...

NCGC607 is a salicylic acid derivative and small molecule glucocerebrosidase (GCase) chaperone. A mutation in the GCase gene is found in patients with Gaucher disease and is the most common genetic risk factor for Parkinson's disease. In induced pluripotent stem cell-derived (iPSC) macrophages from patients with...

Isofagomine (D-tartrate) is a competitive inhibitor of human lysosomal beta-glucosidase (Ki = 0.016-0.025 µM, IC50 = 0.06 µM). By interacting with the catalytic pocket of beta-glucosidase it acts as a chemical chaperone that increases the amount of beta-glucosidase by stabilizing and/or promoting the folding of the...

1-beta-D-Glucosylsphingosine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucocerebrosides (Cay-23207). They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of...

LTI-291 is a CNS-penetrant allosteric activator of glucocerebrosidase (GCase). It increases the activity of wild-type human GCase by 25 and 130% when used at concentrations of 0.1 and 1 µM, respectively.Formal Name: 5,7-dimethyl-N-[trans-4-(pentyloxy)cyclohexyl]-pyrazolo[1,5-a]pyrimidine-3-carboxamide. CAS Number:...