9 products were found matching "K01114"!

Description: Plipastatin A1, a lipopeptide isolated from B. cereus, demonstrates enzyme inhibitory and immunosuppressant properties. It effectively inhibits enzymes phospholipase A2 (PLA2), phospholipase C (PLC), and phospholipase D (PLD) with half-maximal inhibitory concentrations (IC50s) of 2.9, 1.3, and 1.4 µM,...

Description: m-3M3FBS is a phospholipase C (PLC) activator. Target: Apoptosis, Phospholipase. Smiles: Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc1cccc(c1)C(F)(F)F. References: Bae YS, et al. Identification of a compound that directly stimulates phospholipase C activity. Mol Pharmacol. 2003,63(5):1043-1050.

Description: Hydrolyzes sphingomyelin in addition to phosphatidylcholine. PLC-H Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 64.3 kDa and the accession number is P06200.

Description: D609 (Tricyclodecan-9-yl-Xanthogenate) has a wide range of biological activities including antioxidant, antiapoptotic, anticholinergic, antitumor, anti-inflammatory, antiviral, antiproliferative, and neuroprotective activities.D609 acts by inducing competitive inhibition of PC-specific phospholipase C...

Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG). Source: E.coli. Expression Region: 51-436aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Target Protein Sequence: VQHVVILMQE NRSFDHYFGH LNGVRGFNDP RALKRQDGKP VWYQNYKYEF...

D609 is a xanthate and a competitive inhibitor of phosphatidylcholine-specific phospholipase C (PC-PLC, Ki = 6.4 µM). It has no effect on bacterial phosphatidylinositol-specific PLC, bovine pancreatic PLA2, or phospholipase D. D609 reduces sphingomyelin synthase activity by 55.5 and 90.5% in membrane preparations...

m-3M3FBS is a cell permeable and specific activator of phospholipase C (PLC) that has been shown to stimulate the PLC-mediated intracellular Ca2+ release, inositol phosphates production and superoxide generation in various cell types. It activates all PLC isotypes (beta2, beta3, gamma1, gamma2 and delta1) in vitro,...

Plipastatin A1 is a lipopeptide that has been found in B. cereus and has enzyme inhibitory and immunosuppressant activities. It inhibits phospholipase A2 (PLA2), PLC, and PLD (IC50s = 2.9, 1.3, and 1.4 µM, respectively). Plipastatin A1 (100 µg/ml) inhibits LPS-induced B cell blastogenesis and T cell blastogenesis...

Hydrolyzes sphingomyelin in addition to phosphatidylcholine. Source: Recombinant protein corresponding to aa51-436 of Pseudomonas Aeruginosa Hemolytic Phospholipase C, fused to 10xHis-Sumo-Tag at N-terminal and Myc-Tag at C-terminal, expressed in E. coli. Molecular Weight: ~64.3kD, AA Sequence:...