34 products were found matching "K01052"!
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Lalistat 2
Item number: TGM-T41160-500mg
Description: Lalistat 2 is a selective inhibitor of lysosomal acid lipase with IC50 of 152 nM and exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein lipase (up to 10 µM). Target: Lipase. Smiles: O=C(Oc1nsnc1N1CCCCC1)N1CCCCC1. References: Rosenbaum et al (2009) Chemical screen to reduce...
| Application: | Lysosomal acid lipase inhibitor |
| CAS | 1234569-09-5 |
| MW: | 296.39 D |
From 40.00€
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Lalistat 1
Item number: TGM-T38344-100mg
Description: Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM) and IgA1 protease for H. influenzae. Lalistat 1 can be used in studies about niemann-pick type C diseases. Target: Antibacterial. Smiles: O=C(Oc1nsnc1N1CCCCC1)N1CCOCC1. References: Rosenbaum, A.I., Rujoi, M., Huang, A.Y., et al....
| Keywords: | ZINC795230 |
| Application: | LAL inhibitor |
| CAS | 501104-16-1 |
| MW: | 298.36 D |
From 46.00€
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4-Methylumbelliferyl palmitate
Item number: TGM-T83314-100mg
Description: 4-Methylumbelliferyl palmitate serves as a potent fluorophore to assay acid lipase activity in human leukocytes, with its fluorescence significantly affected by acidity and solvent properties. In near-neutral aqueous solutions, it predominates in a neutral molecular form, emitting strong fluorescence at...
| Application: | Fluorogenic LAL / Cholesteryl esterase substrate |
| CAS | 17695-48-6 |
| MW: | 414.58 D |
From 192.00€
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LIPA Protein, Human, Recombinant (His)
Item number: TGM-TMPH-01625-100ug
Description: Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 45.0 kDa and the accession...
| Keywords: | Sterol esterase, Cholesteryl esterase, Lysosomal acid lipase/cholesteryl ester hydrolase, LIPA, Lipase A |
| MW: | 45.0 kD |
From 229.00€
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LIPA Protein, Human, Recombinant (GST)
Item number: TGM-TMPH-01626-100ug
Description: Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 70.0 kDa...
| Keywords: | Lipase A, Lysosomal acid lipase/cholesteryl ester hydrolase, Sterol esterase, Cholesteryl esterase, LIPA |
| MW: | 70.0 kD |
From 198.00€
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4-Methylumbelliferyl Palmitate
Item number: Cay16089-100
Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase (LAL), also known as cholesteryl ester hydrolase. 4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL). 4-MUP is cleaved by LAL to...
| Keywords: | 4-MU Palmitate, 4-MUP, Palmitoyl 4-Methylumbelliferone, hexadecanoic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester |
| Application: | Fluorogenic LAL / Cholesteryl esterase substrate |
| CAS | 17695-48-6 |
| MW: | 414.6 D |
From 106.00€
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Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA),...
Item number: CSB-EP012972HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 22-399aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal GST-tagged. Target Protein Sequence: SGGKLTAVDP ETNMNVSEII SYWGFPSEEY LVETEDGYIL CLNRIPHGRK NHSDKGPKPV VFLQHGLLAD SSNWVTNLAN SSLGFILADA GFDVWMGNSR GNTWSRKHKT LSVSQDEFWA...
| Keywords: | LAL, LIPA, Lipase A, Sterol esterase, Cholesteryl esterase, Acid cholesteryl ester hydrolase, Lysosomal acid... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 70 kD |
From 219.00€
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Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA),...
Item number: CSB-EP012972HUa0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 22-399aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: SGGKLTAVDP ETNMNVSEII SYWGFPSEEY LVETEDGYIL CLNRIPHGRK NHSDKGPKPV VFLQHGLLAD SSNWVTNLAN SSLGFILADA GFDVWMGNSR GNTWSRKHKT LSVSQDEFWA...
| Keywords: | LAL, LIPA, Lipase A, Sterol esterase, Cholesteryl esterase, Acid cholesteryl ester hydrolase, Lysosomal acid... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 47.1 kD |
From 219.00€
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Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA),...
Item number: CSB-YP012972HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 22-399aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: SGGKLTAVDP ETNMNVSEII SYWGFPSEEY LVETEDGYIL CLNRIPHGRK NHSDKGPKPV VFLQHGLLAD SSNWVTNLAN SSLGFILADA GFDVWMGNSR GNTWSRKHKT LSVSQDEFWA...
| Keywords: | LAL, LIPA, Lipase A, Sterol esterase, Cholesteryl esterase, Acid cholesteryl ester hydrolase, Lysosomal acid... |
| Application: | Activity not tested |
| Expressed in: | Yeast |
| Origin: | human |
| MW: | 45 kD |
From 242.00€
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Lalistat 2
Item number: Cay25347-5
Lalistat 2 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 152 nM using purified human LAL). It blocks lipid clearance induced by the autophagy enhancers MSL and MSL-7 in HeLa cells preloaded with palmitic acid (Cay-10006627) and oleic acid (Cay-90260).Formal Name: 1-piperidinecarboxylic acid,...
| Keywords: | 1-piperidinecarboxylic acid, 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester |
| Application: | Lysosomal acid lipase inhibitor |
| CAS | 1234569-09-5 |
| MW: | 296.4 D |
From 116.00€
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4-Methylumbelliferyl Oleate
Item number: Cay19590-50
4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases. It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.Formal Name:...
| Keywords: | 4-Methylumbelliferone Oleate, 4-MU Oleate, 4-MUO, 7-hydroxy-4-Methylcoumarin Oleate, 9Z-octadecenoic... |
| Application: | Fluorogenic lipase substrate |
| CAS | 18323-58-5 |
| MW: | 440.6 D |
From 66.00€
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Lalistat 1
Item number: Cay23891-1
Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM using purified human LAL). It is selective for LAL over human pancreatic and bovine milk lipoprotein lipases up to a concentration of 10 µM. Lalistat 1 (0.01-10 µM) reduces cholesterol accumulation in lysosome-like storage organelles in GM03123...
| Keywords: | 4-morpholinecarboxylic acid, 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester |
| Application: | LAL inhibitor |
| CAS | 501104-16-1 |
| MW: | 298.4 D |
From 61.00€
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