10 products were found matching "K00706"!

Description: MK 3118, a glucan synthase inhibitor, is used potentially for the treatment of candida infection and aspergillosis. Target: Others. Smiles:...

Description: Echinocandin B is a cyclic hexapeptide echinocandin antibiotic from Aspergillus nidulans var. echinulatus . It attacks the cell wall of fungi by inhibiting beta-1,3-glucan synthesis. Target: Others. Smiles:...

Description: Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent. Target: Antibiotic, Antifungal. Smiles:...

Caspofungin is an echinocandin antifungal originally isolated from G. lozoyensis and a derivative of pneumocandin B0 (Cay-21527). It is active against 3,959 Candida clinical isolates (MIC90 = 1 µg/ml), including isolates resistant to fluconazole (Cay-11594) or itraconazole (Cay-13288), as well as 38 Aspergillus...

Caspofungin acetate is a lipopeptide antifungal that inhibits the enzyme 1,3-beta-Glucan synthase, which synthesizes -glucan polymers that form fungal cell walls. Caspofungin acetate is active against a variety of Aspergillus and Candida species and unlike many antifungals, is not metabolized by the cytochrome p450...

Micafungin is an echinocandin antifungal that inhibits 1,3-beta-D-glucan synthesis. It has fungicidal activity against virtually all species of Candida, including those resistant to fluconazole, and is fungistatic against Aspergillus spp.Formal Name:...

Anidulafungin is a semisynthetic echinocandin antifungal. It inhibits 1,3-beta-D glucan synthase from several C. albicans clinical isolates (IC50s = 0.89-7.96 ng/ml for the wild-type enzyme). Anidulafungin is active against various Candida species, including C. albicans, C. parapsilosis, C. tropicalis, and C....

Pneumocandin B0 is an antifungal lipopeptide that acts by inhibiting the synthesis of beta-(1,3)-D-glucan, a component of fungal cell walls (IC50s = 70 and 67 ng/ml for inhibiting glucan synthase in C. albicans and A. fumigatus, respectively). It can be used to synthesize the echinocandin caspofungin...

Caspofungin-d4 (acetate) is intended for use as an internal standard for the quantification of caspofungin (Cay-15923) by GC- or LC-MS. Caspofungin is an antifungal compound that is classified as an echinocandin, as it acts by noncompetititvely inhibiting the enzyme 1,3-beta glucan synthase and preventing the...

Echinocandin B is an echinocandin antifungal originally isolated from Aspergillus. Echinocandin B is an inhibitor of 1,3-beta glucan synthase, and it inhibits incorporation of radiolabeled glucose into alkali-insoluble glucan by S. cerevisiae spheroplasts in a dose-dependent manner. It inhibits growth of C. albicans...