15 products were found matching "K00706"!

Micafungin, an echinocandin, exhibits fungicidal and fungistatic activities through the inhibition of 1,3-beta-D-glucan synthesis. It was also found to have antiviral effects against various viruses including the coronavirus SARS-CoV-2 and its variants. SMILES:...

Description: MK 3118, a glucan synthase inhibitor, is used potentially for the treatment of candida infection and aspergillosis. Target: Others. Smiles:...

Description: Echinocandin B is a cyclic hexapeptide echinocandin antibiotic from Aspergillus nidulans var. echinulatus . It attacks the cell wall of fungi by inhibiting beta-1,3-glucan synthesis. Target: Others. Smiles:...

Description: Caspofungin is a cyclic lipopeptide echinocandin and beta-(1,3)-D-glucan synthase inhibitor that is used to treat internal or systemic mycoses. Target: Others. Smiles:...

Description: Ibrexafungerp citrate is a triterpenoid antifungal. Similarly to echinocandins, it inhibits the synthesis of 1,3-beta-d-glucan. However, it binds to a different site on the enzyme than echinocandins, resulting in limited cross-resistance. Ibrexafungerp exerts concentration-dependent fungicidal activity...

Description: Micafungin sodium (FK 463) is the sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antifungal activity. Target: Antifungal, Antibiotic. Smiles:...

Description: Caspofungin Acetate (MK 0991) is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. This agent is active against Aspergillus and Candida species. Target: Antibiotic, Antifungal. Smiles:...

Description: Anidulafungin (Ecalta) (LY303366) is an echinocandin derivative used as an antifungal drug. It inhibits glucan synthase activity. Target: Antifungal, Antibiotic, Others. Smiles:...

Caspofungin is an echinocandin antifungal originally isolated from G. lozoyensis and a derivative of pneumocandin B0 (Cay-21527). It is active against 3,959 Candida clinical isolates (MIC90 = 1 µg/ml), including isolates resistant to fluconazole (Cay-11594) or itraconazole (Cay-13288), as well as 38 Aspergillus...

Caspofungin acetate is a lipopeptide antifungal that inhibits the enzyme 1,3-beta-Glucan synthase, which synthesizes -glucan polymers that form fungal cell walls. Caspofungin acetate is active against a variety of Aspergillus and Candida species and unlike many antifungals, is not metabolized by the cytochrome p450...

Micafungin is an echinocandin antifungal that inhibits 1,3-beta-D-glucan synthesis. It has fungicidal activity against virtually all species of Candida, including those resistant to fluconazole, and is fungistatic against Aspergillus spp.Formal Name:...

Anidulafungin is a semisynthetic echinocandin antifungal. It inhibits 1,3-beta-D glucan synthase from several C. albicans clinical isolates (IC50s = 0.89-7.96 ng/ml for the wild-type enzyme). Anidulafungin is active against various Candida species, including C. albicans, C. parapsilosis, C. tropicalis, and C....