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Bisphenol A-beta-D-Glucuronide
Item number: Cay35857-1
Bisphenol A-beta-D-glucuronide (BPA-glucuronide) is an inactive metabolite of the plasticizer BPA. It is formed from BPA primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT2B15. Unlike BPA, BPA-glucuronide does not bind to estrogen receptors (ERs) in cell-free assays or induce ER-mediated transcription in...
| Keywords: | BPA-glucuronide, BPAG, BPA-monoglucuronide, BPA-beta-D-glucuronide, beta-D-glucopyranosiduronic acid,... |
| Application: | Inactive BPA metabolite |
| CAS | 267244-08-6 |
| MW: | 404.4 D |
From 239.00€
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Trifluoperazine N-Glucuronide
Item number: TGM-T29009-1mg
Description: Trifluoperazine N-Glucuronide is a metabolite of Trifluoperazine with antidepressant and antipsychotic activity. Target: Others. Smiles: C(CCN1CC[N@@+](C)(CC1)[C@@H]2O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]2O)N3C=4C(SC=5C3=CC=CC5)=CC=C(C(F)(F)F)C4. References: Kim HJ, Jeong ES, Seo KA, Shin KJ, Choi YJ,...
| Application: | Trifluoperazine metabolite |
| CAS | 165602-90-4 |
| MW: | 583.62 D |
From 536.00€
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all-trans Retinoyl beta-D-Glucuronide
Item number: TGM-T35952-2mg
Description: all-trans Retinoyl beta-D-glucuronide is a metabolite of all-trans retinoic acid formed by the UDP-glucuronosyltransferase (UGT) system. It is rapidly converted to all-trans retinoic acid following in vitro or in vivo administration. Target: Others. Smiles:...
| Application: | Metabolite |
| CAS | 401-10-5 |
| MW: | 476.566 D |
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Diosgenin glucoside
Item number: TGM-T3874-100mg
Description: Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis. Significant inhibition of Diosgenin glucoside synthesis and stimulation of solasodine glucosylation was found only with PC molecular species...
| Keywords: | Disogluside, Trillin |
| Application: | Bioactive steroidal saponin |
| CAS | 14144-06-0 |
| MW: | 576.76 D |
From 54.00€
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Estriol 3-beta-D-Glucuronide (sodium salt)
Item number: TGM-T37005-10mg
Description: Estriol 3-beta-D-glucuronide is a metabolite of estriol . It is formed from estriol by the UDP-glucuronosyltransferase (UGT) isoform UGT1A10. Estriol 3-beta-D-glucuronide binds to basolateral and canalicular liver plasma membranes with Kd values of 85 and 164 µM, respectively. It competitively inhibits...
| Application: | Estriol metabolite (UGT1A10) |
| CAS | 15087-06-6 |
| MW: | 487.501 D |
From 529.00€
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Etodolac Acyl Glucuronide
Item number: TGM-T37117-1mg
Description: Etodolac acyl glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor etodolac .1It is formedviaglucuronidation of etodolac by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A9, UGT1A10, and UGT2B7. Target: Others. Smiles:...
| Application: | Etodolac phase II metabolite |
| CAS | 79541-43-8 |
| MW: | 463.483 D |
475.00€
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Propofol beta-D-Glucuronide
Item number: TGM-T37378-10mg
Description: Propofol beta-D-glucuronide is a metabolite of propofol sulfate, a short-acting anesthetic agent. The metabolite is generated through the glucuronidation of propofol by uridine diphosphate glucuronosyltransferases, and propofol metabolism appears to occur more rapidly in women than in men. [1] [2]....
| Application: | Propofol sulfate metabolite |
| CAS | 114991-26-3 |
| MW: | 354.39 D |
From 77.00€
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1-Salicylate Glucuronide
Item number: TGM-T37484-1mg
Description: 1-Salicylate glucuronide is a metabolite of salicylic acid and aspirin .1It is formed from salicylic acid primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A9 but also by a variety of other UGT isoforms and from aspirinviasalicylic acid as an intermediate. Target: Others. Smiles:...
| Application: | Salicylic acid / aspirin metabolite |
| CAS | 7695-70-7 |
| MW: | 314.246 D |
From 166.00€
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Bavachalcone
Item number: TGM-T3S0137-10mg
Description: Bavachalcone, a major bioactive compound isolated from *Psoralea corylifolia* L., may serve as a therapeutic drug for bone resorption-associated diseases. It protects endothelial function by increasing AMPK activity and MnSOD expression while reducing mitochondrial oxidative stress. Target:...
| Application: | Bioactive chalcone, flavonoid |
| CAS | 28448-85-3 |
| MW: | 324.37 D |
From 51.00€
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Gitogenin
Item number: TGM-T3S0860-100mg
Description: 1. Gitogenin, tigogenin, and solasodine are novel selective inhibitors of UGT1A4, and do not inhibit the activities of major human CYP isoforms. 2. Gitogenin and (25S)-5alpha-furastan-3beta, 22, 26-triol are the inhibitors of enzyme alpha-glucosidase with IC50 values of 37.2±0.18 and 33.5±0.22 uM,...
| Application: | Sapogenin, UGT1A4 inhibitor, growth hormone-releasing agent |
| CAS | 511-96-6 |
| MW: | 432.64 D |
From 88.00€
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Acetaminophen Glucuronide (sodium salt)
Item number: TGM-T36826-10mg
Description: Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen . It is formed via glucuronidation of acetaminophen by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A6, UGT1A9, UGT1A1, and UGT2B15. Target: Others. Smiles:...
| Application: | Inactive metabolite |
| CAS | 120595-80-4 |
| MW: | 350.279 D |
From 108.00€
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SN-38 glucuronide
Item number: TGM-T73905-1mg
Description: SN-38 glucuronide, an inactive metabolite of Irinotecan, serves as a derivative of this cancer-fighting agent. Irinotecan, known for inhibiting topoisomerase I, is utilized in the research of colon and rectal cancer [1]. Target: Others. Smiles:...
| Application: | Irinotecan phase II metabolite |
| CAS | 121080-63-5 |
| MW: | 568.53 D |
1,314.00€
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