82 products were found matching "K00665"!
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TVB-3166
Item number: TGM-T17180-100mg
Description: TVB-3166 induces apoptosis and inhibits in-vivo xenograft tumor growth. TVB-3166 is a reversible and selective fatty acid synthase inhibitor (IC50s: 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively). Target: Apoptosis, Fatty Acid Synthase, Others. Smiles:...
| Application: | FASN inhibitor |
| CAS | 1533438-83-3 |
| MW: | 384.47 D |
From 34.00€
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BI 99179
Item number: TGM-T14570-2mg
Description: BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM and it exhibits significant exposure (both peripheral and central) upon oral administration in rats[1]. Target: Fatty Acid Synthase. Smiles: CCC(=O)N[C@H]1CC[C@H](C1)C(=O)N(C)c1ccc(cc1)-c1nc2ccccc2o1....
| Keywords: | BI99179 |
| Application: | FAS-I inhibitor |
| CAS | 1291779-76-4 |
| MW: | 391.46 D |
46.00€
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GSK2194069
Item number: TGM-T15429-2mg
Description: GSK2194069 is an active beta-keto reductase (KR)-specific inhibitor of fatty acid synthase (FASN) with an IC50 of 7.7 nM in an assay for the detection of released CoA.GSK2194069 inhibits the proliferation of FAS in cancer cells through the action of acetoacetyl-coenzyme A and NADPH. Target: Others,...
| Application: | FASN inhibitor |
| CAS | 1332331-08-4 |
| MW: | 428.48 D |
146.00€
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Icaritin
Item number: TGM-T3398-100mg
Description: Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Icaritin has anti-multiple myeloma activity, mainly mediated by inhibiting...
| Keywords: | Cycloicaritin, Anhydroicaritin |
| Application: | Anticancer agent, fatty acid synthase inhibitor |
| CAS | 118525-40-9 |
| MW: | 368.38 D |
From 31.00€
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Malonyl Coenzyme A lithium
Item number: TGM-T38473-10mg
Description: Malonyl Coenzyme A (lithium) is a coenzyme A derivative that is utilized in fatty acid and polyketide synthesis and in the transport of alpha-ketoglutarate across the mitochondrial membrane. Malonyl Coenzyme A (lithium) is formed by the Acetyl CoA Carboxylase-mediated carboxylation of acetyl CoA....
| Application: | Fatty acid & polyketide synthesis intermediate |
| CAS | 108347-84-8 |
| MW: | 860.52 D |
From 108.00€
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Avicularin
Item number: TGM-T6S0117-10mg
Description: Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-kappaB(p65), COX-2, and PPAR-gamma. In LPS-stimulated RAW 264.7 macrophages, it exerts...
| Keywords: | Fenicularin |
| Application: | Bioactive flavonoid glycoside |
| CAS | 572-30-5 |
| MW: | 434.35 D |
From 61.00€
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FT113
Item number: TGM-T7947-100mg
Description: FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity. Target: Fatty Acid Synthase. Smiles: OC1(CC1)C(=O)N1CCN(CC1)C(=O)c1ccc(cc1)-c1nc2ccc(F)cc2o1. References: Martin MW, et al. Discovery and optimization of novel piperazines as potent...
| Application: | FASN inhibitor |
| CAS | 1630808-89-7 |
| MW: | 409.41 D |
From 33.00€
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Fasnall benzenesulfonate
Item number: TGM-T85305-10mg
Description: Fasnall, a fatty acid synthase (FASN) inhibitor, exhibits an IC50 of 3.71 µM against the human recombinant enzyme. It halts tritiated acetate incorporation into lipids (IC50= 5.84 µM), boosts ceramide levels, and triggers lipid droplet formation in BT474 HER2+ breast cancer cells. Demonstrating...
| Application: | FASN / FAS inhibitor |
| CAS | 2187367-11-7 |
| MW: | 496.6 D |
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FASN Protein, Human, Recombinant (His)
Item number: TGM-TMPY-06683-500ug
Description: FASN Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35.26 kDa and the accession number is P49327.
| Keywords: | SDR27X1, FAS, fatty acid synthase, OA-519 |
| MW: | 35.26 kD |
From 587.00€
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FASN Protein, Mouse, Recombinant (His)
Item number: TGM-TMPY-06686-500ug
Description: FASN Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.23 kDa and the accession number is P19096.
| Keywords: | fatty acid synthase, FAS, A630082H08Rik |
| MW: | 34.23 kD |
From 587.00€
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Anti-FASN
Item number: CSB-PA002507.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-FAS, Anti-FASN, Anti-Fatty acid synthase, Anti-Type I fatty acid synthase, Anti-Acyl-[acyl-carrier-protein]... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 125.00€
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Anti-FASN
Item number: CSB-PA13179A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: FASN. Antigen Species: Human
| Keywords: | Anti-FAS, Anti-FASN, Anti-Fatty acid synthase, Anti-Type I fatty acid synthase, Anti-Acyl-[acyl-carrier-protein]... |
| Application: | ELISA, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human |
From 165.00€
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