40 products were found matching "K00511"!

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Terbinafine
Terbinafine

Item number: TGM-T6702-100mg

Description: Terbinafine (TDT 067) is a synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important component of fungal cell membranes. As a result, this agent disrupts fungal cell...
Keywords: SF 86-327, Terbinex, Lamisil, TDT 067
Application: Targets squalene monooxygenase [EC:1.14.14.17] (SQLE, ERG1)
CAS 91161-71-6
MW: 291.43 D
From 40.00€ *
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Butenafine hydrochloride
Butenafine hydrochloride

Item number: TGM-T1217-1g

Description: Butenafine hydrochloride (KP363 Hydrochloride) is a synthetic benzylamine antifungal, inhibiting the synthesis of sterols by inhibiting squalene epoxidase. Target: Antibiotic, Antifungal. Smiles: Cl.C(c1ccc(cc1)CN(C)Cc1cccc2c1cccc2)(C)(C)C. References: Kokjohn K, et al. Int J Dermatol, 2003, 42, 11-17.
Keywords: KP-363, KP363 (Hydrochloride), Butenafine HCl
Application: Targets squalene monooxygenase [EC:1.14.14.17] (SQLE, ERG1)
CAS 101827-46-7
MW: 353.93 D
From 31.00€ *
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Liranaftate
Liranaftate

Item number: TGM-T1497-100mg

Description: Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is essential for cell membrane integrity. By preventing ergosterol synthesis and...
Keywords: Piritetrate, M-732
Application: Targets squalene monooxygenase [EC:1.14.14.17] (SQLE, ERG1)
CAS 88678-31-3
MW: 328.43 D
From 49.00€ *
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Tolciclate
Tolciclate

Item number: TGM-T24893-100mg

Description: Tolciclate is an agent of antifungal medication. Target: Others. Smiles: O(C(N(C)C1=CC(C)=CC=C1)=S)C=2C=C3C(C4CC3CC4)=CC2. References: Cucè LC, Assunção BF, Medawar LG, Salibian A, Groppi W. Tolciclate versus miconazole, a double-blind trial in patients with dermatomycosis. J Int Med Res....
Application: Targets squalene monooxygenase [EC:1.14.14.17] (SQLE, ERG1)
CAS 50838-36-3
MW: 323.45 D
From 1,520.00€ *
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Butenafine
Butenafine

Item number: TGM-T21365-25mg

Description: Butenafine hydrochloride is a hydrochloride of butenafine, which inhibits squalene epoxidase to inhibit the synthesis of ergosterol, leading to the increased permeability of the cell membranes, allowing their contents to leak out. Target: Others. Smiles: C=1C=CC2=C(C1)C=CC=C2CN(C)CC3=CC=C(C=C3)C(C)(C)C....
Keywords: KP-363, Butop, KP 363, Mentax, KP363
Application: Targets squalene monooxygenase [EC:1.14.14.17] (SQLE, ERG1)
CAS 101828-21-1
MW: 317.47 D
1,520.00€ *
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Corilagin
Corilagin

Item number: TGM-T3795-100mg

Description: Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.Corilagin can enhance the cytotoxicity of both cisplatin and doxorubicin on the Hep3B hepatoma cells.Corilagin has antiviral activity, reduces the cytotoxicity induced...
Application: Squalene epoxidase inhibitor
CAS 23094-69-1
MW: 634.45 D
From 43.00€ *
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Terbinafine-d3 hydrochloride
Terbinafine-d3 hydrochloride

Item number: TGM-TMID-0249-1mg

Description: Terbinafine-d3 hydrochloride is a deuterated compound of Terbinafine hydrochloride. Terbinafine hydrochloride has a CAS number of 78628-80-5. Terbinafine Hydrochloride is a synthetic allylamine derivative structurally related to naftifine. Terbinafine is active against dermatophytes. Smiles:...
Application: GC-MS, LC-MS, quantification, internal standard, antifungal, ergosterol biosynthesis inhibitor
CAS 1310012-15-7
MW: 330.91 D
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NB-598
NB-598

Item number: TGM-TQ0115-100mg

Description: NB-598 is an effective and competitive inhibitor of squalene epoxidase. It suppresses triglyceride biosynthesis through the farnesol pathway. Target: Antifungal. Smiles: CCN(C\C=C\C#CC(C)(C)C)Cc1cccc(OCc2cc(cs2)-c2ccsc2)c1. References: Horie M, et al. Effects of NB-598, a potent squalene epoxidase...
Application: Squalene epoxidase inhibitor
CAS 131060-14-5
MW: 449.67 D
From 72.00€ *
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Squalene monooxygenase (SQLE), partial, human, recombinant
Squalene monooxygenase (SQLE), partial, human, recombinant

Item number: CSB-EP613505HU1.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 42-574aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: LSYRCRHRNG GLLGRQQSGS QFALFSDILS GLPFIGFFWA KSPPESENKE QLEARRRRKG TNISETSLIG TAACTSTSSQ NDPEVIIVGA GVLGSALAAV LSRDGRKVTV IERDLKEPDR IVGEFLQPGG YHVLKDLGLG...
Keywords: SE, SQLE, ERG1, Squalene epoxidase, Squalene monooxygenase, Recombinant Human Squalene monooxygenase (SQLE), partial
Application: Activity not tested
Expressed in: E.coli
Origin: human
MW: 63.3 kD
From 292.00€ *
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Terbinafine (hydrochloride)
Terbinafine (hydrochloride)

Item number: Cay10011619-100

Terbinafine is a broad-spectrum antifungal agent that has activity against T. rubrum, T. metagrophytes, T. verrucosum, E. floccosum, M. canis, A. fumigatus, and S. schenckii (MIC50s = 0.003-0.8 µg/ml). It selectively inhibits C. albicans squalene epoxidase over rat liver epoxidase (IC50s = 0.03 and 77 µM,...
Keywords: N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine, monohydrochloride
Application: Antifungal compound, ergosterol biosynthesis inhibitor
CAS 78628-80-5
MW: 327.9 D
From 100.00€ *
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Naftifine (hydrochloride)
Naftifine (hydrochloride)

Item number: Cay19234-50

Naftifine is an allylamine compound that blocks ergosterol biosynthesis in fungi by inhibiting squalene epoxidase (Ki = 1.1 µM for C. albicans epoxidase).Formal Name: N-methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-1-naphthalenemethanamine, monohydrochloride. CAS Number: 65473-14-5. Synonyms: AW 105-843. Molecular Formula:...
Keywords: AW 105-843, N-methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-1-naphthalenemethanamine, monohydrochloride
Application: Squalene epoxidase inhibitor
CAS 65473-14-5
MW: 323.9 D
From 53.00€ *
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Amorolfine (hydrochloride)
Amorolfine (hydrochloride)

Item number: Cay26077-100

Amorolfine is an antifungal. It is active against isolates of T. rubrum, T. mentagrophytes, and C. albicans (MIC90s = 4-15, 4-60, and =30-500 ng/ml, respectively). It inhibits the growth of T. mentagrophytes and T. rubrum by 33.7 and 38.5%, respectively, in an in vitro bovine hoof model of onychomycosis. Amorolfine...
Keywords: Ro 14-4767/002, (2R,6S)-rel-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine, monohydrochloride
Application: Antifungal, ergosterol biosynthesis inhibitor
CAS 78613-38-4
MW: 354 D
From 85.00€ *
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