- Search results for K00511
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32 products were found matching "K00511"!
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Item number: CSB-EP613505HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 42-574aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: LSYRCRHRNG GLLGRQQSGS QFALFSDILS GLPFIGFFWA KSPPESENKE QLEARRRRKG TNISETSLIG TAACTSTSSQ NDPEVIIVGA GVLGSALAAV LSRDGRKVTV IERDLKEPDR IVGEFLQPGG YHVLKDLGLG...
Keywords: | SE, SQLE, ERG1, Squalene epoxidase, Squalene monooxygenase, Recombinant Human Squalene monooxygenase (SQLE), partial |
Application: | Activity not tested |
Expressed in: | E.coli |
Origin: | human |
MW: | 63.3 kD |
From 283.00€
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Item number: ELK-ELK4164.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SQLE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SQLE. Next,...
Keywords: | SE, SQLE, ERG1, Squalene epoxidase, Squalene monooxygenase |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: Cay10011619-100
Terbinafine is a broad-spectrum antifungal agent that has activity against T. rubrum, T. metagrophytes, T. verrucosum, E. floccosum, M. canis, A. fumigatus, and S. schenckii (MIC50s = 0.003-0.8 µg/ml). It selectively inhibits C. albicans squalene epoxidase over rat liver epoxidase (IC50s = 0.03 and 77 µM,...
Keywords: | N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine, monohydrochloride |
Application: | Antifungal compound, Ergosterol biosynthesis inhibitor |
CAS | 78628-80-5 |
MW: | 327.9 D |
From 98.00€
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Item number: Cay19234-50
Naftifine is an allylamine compound that blocks ergosterol biosynthesis in fungi by inhibiting squalene epoxidase (Ki = 1.1 µM for C. albicans epoxidase).Formal Name: N-methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-1-naphthalenemethanamine, monohydrochloride. CAS Number: 65473-14-5. Synonyms: AW 105-843. Molecular Formula:...
Keywords: | AW 105-843, N-methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-1-naphthalenemethanamine, monohydrochloride |
Application: | Squalene epoxidase inhibitor |
CAS | 65473-14-5 |
MW: | 323.9 D |
From 52.00€
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Item number: Cay26077-100
Amorolfine is an antifungal. It is active against isolates of T. rubrum, T. mentagrophytes, and C. albicans (MIC90s = 4-15, 4-60, and =30-500 ng/ml, respectively). It inhibits the growth of T. mentagrophytes and T. rubrum by 33.7 and 38.5%, respectively, in an in vitro bovine hoof model of onychomycosis. Amorolfine...
Keywords: | Ro 14-4767/002, (2R,6S)-rel-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine, monohydrochloride |
Application: | Antifungal, Ergosterol biosynthesis inhibitor |
CAS | 78613-38-4 |
MW: | 354 D |
From 84.00€
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Item number: Cay21446-1
Tolnaftate is a thiocarbamate antifungal agent. It is active against clinical isolates of the dermatophytes T. rubrum, T. mentagraphytes, T. verrucosum, E. floccosum, and M. canis (MIC50s = 50, 100, 6, 50, and 50 ng/ml, respectively), as well as 18 additional yeast and filamentous fungi species (MIC = 0.003-0.8...
Keywords: | NSC 233648, SCH 10144, N-methyl-N-(3-methylphenyl)-carbamothioic acid, O-2-naphthalenyl ester |
Application: | Antifungal, Ergosterol biosynthesis inhibitor |
CAS | 2398-96-1 |
MW: | 307.4 D |
From 52.00€
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Item number: Cay14912-5
NB-598 is an inhibitor of squalene epoxidase (IC50s = 2 and 0.75 nM for dog liver and human microsomal enzymes, respectively). It selectively inhibits cholesterol synthesis over free fatty acid, triglyceride, and phospholipid synthesis in HepG2 cells at 1 µM. NB-598 (10 mg/kg per day) reduces serum cholesterol...
Keywords: | 3-([3,3'-bithiophen]-5-ylmethoxy)-N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-ethyl-benzenemethanamine |
Application: | Squalene epoxidase inhibitor |
CAS | 131060-14-5 |
MW: | 449.7 D |
From 35.00€
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-30 %
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Item number: ARG57421.100
Protein function: Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway. [The UniProt Consortium]
Keywords: | Anti-SE, Anti-ERG1, Anti-SQLE, EC=1.14.14.17, Anti-Squalene epoxidase, Anti-Squalene monooxygenase |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
624.00€
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436.80€
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Item number: Cay14001-10
Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor. Alliin exhibits anti-cancer, anti-microbial, anti-hypertensive, cardioprotective, and anti-oxidant activities. It has been shown to inhibit squalene monooxygenase, a...
Keywords: | (±)-Allyl-L-cysteine sulfoxide, S-2-propen-1-yl-S-oxide-L-cysteine |
Application: | Metabolic studies |
CAS | 17795-26-5 |
MW: | 177.2 D |
From 114.00€
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Item number: Cay11832-1
Corilagin is a polyphenol and hydrolyzable tannin that can be isolated from a variety of plants. It inhibits squalene epoxidase (IC50 = 4.0 µM), a key enzyme in cholesterol synthesis. Corilagin also has various anti-inflammatory and anti-cancer effects.Formal Name: cyclic...
Keywords: | cyclic 3,6-[(1R)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate]... |
Application: | Squalene epoxidase inhibitor |
CAS | 23094-69-1 |
MW: | 634.5 D |
From 43.00€
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Item number: Cay23797-1
Butenafine is a benzylamine antifungal agent that has broad-spectrum activity against 87 strains of dermatophytes (MICs = 0.0015-0.05 µg/ml), 15 strains of Aspergillus (MICs = 0.025-0.78 µg/ml), 4 strains of Cryptococcus (MICs = 0.78-1.56 µg/ml), and 67 strains of Candida (MICs = 3.13 to >100 µg/ml). It acts by...
Keywords: | N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-1-naphthalenemethanamine, monohydrochloride |
Application: | Antifungal, ergosterol biosynthesis inhibitor, squalene epoxidase inhibitor |
CAS | 101827-46-7 |
MW: | 353.9 D |
From 66.00€
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Item number: LKT-T1672.1
Allylamine, squalene oxidase and KSR1 inhibitor.
Keywords: | Lamisil, N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1- naphthalenemethanamine hydrochloride |
Application: | Anticancer agent, Squalene epoxidase inhibitor |
CAS | 78628-80-5 |
MW: | 327,9 D |
From 94.00€
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