96 products were found matching "K00254"!
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Dihydroorotate dehydrogenase (quinone), mitochondrial...
Item number: CSB-EP714357RA1c2.1
Organism: Rattus norvegicus (Rat). Source: E.coli. Expression Region: 31-395aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-Trx-tagged. Target Protein Sequence: TGDDHFYAEY LMPGLQRLLD PESAHRLAVR VTSLGLLPRA TFQDSDMLEV KVLGHKFRNP VGIAAGFDKN GEAVDGLYKL GFGFVEVGSV TPQPQEGNPR PRVFRLPEDQ AVINRYGFNS HGLSVVEHRL...
| Keywords: | Dhodh, DHOdehase, Dihydroorotate oxidase, Dihydroorotate dehydrogenase (quinone), mitochondrial |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | rat |
| MW: | 57.6 kD |
From 364.00€
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Olorofim
Item number: TGM-T27300-1mg
Description: Olorofim is a novel selective antifungal compound with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM) and almost no inhibitory effect on human DHODH (>100 uM).Olorofim has good efficacy against various pathogenic filamentous and dimorphic fungi such as Penicillium spp, Dermatophilus spp...
| Keywords: | Olorofim, F901318, F-901318 |
| Application: | Targets dihydroorotate dehydrogenase [EC:1.3.5.2] (DHODH, pyrD) |
| CAS | 1928707-56-5 |
| MW: | 498.55 D |
From 389.00€
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Brequinar
Item number: TGM-T5013-100mg
Description: Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses. Target: Dehydrogenase, DNA/RNA Synthesis, Virus Protease. Smiles: Cc1c(nc2ccc(F)cc2c1C(O)=O)-c1ccc(cc1)-c1ccccc1F. References: Qing M, et al. Characterization of...
| Keywords: | Bipenquinate, NSC 368390, DUP785 |
| Application: | DHODH inhibitor |
| CAS | 96187-53-0 |
| MW: | 375.37 D |
From 42.00€
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Teriflunomide
Item number: TGM-T7534-100mg
Description: Teriflunomide (A 77-1726) is the principal active metabolite of leflunomide, an approved therapy for rheumatoid arthritis and multiple sclerosis. Target: Others. Smiles: C(F)(F)(F)C1=CC=C(NC(/C(=C(/C)\O)/C#N)=O)C=C1. References: Paul O , Oh . An update of teriflunomide for treatment of multiple...
| Keywords: | A 77-1726 |
| Application: | Targets dihydroorotate dehydrogenase [EC:1.3.5.2] (DHODH, pyrD) |
| CAS | 163451-81-8 |
| MW: | 270.21 D |
From 45.00€
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Bipenquinate
Item number: TGM-T8332-100mg
Description: Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis. Target: Dehydrogenase. Smiles: [Na+].Cc1c(nc2ccc(F)cc2c1C([O-])=O)-c1ccc(cc1)-c1ccccc1F. References: Li S F , Gong M J , Sun Y F , et al. Antiviral...
| Application: | Targets dihydroorotate dehydrogenase [EC:1.3.5.2] (DHODH, pyrD) |
| CAS | 96201-88-6 |
| MW: | 397.36 D |
From 31.00€
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AG-636
Item number: TGM-T9121-100mg
Description: AG-636 is a potent, reversible, and selective DHODH inhibitor with an IC50 of 17 nM and is orally active. It demonstrates strong anticancer effects. Target: DNA/RNA Synthesis, Dehydrogenase. Smiles: Cc1ccccc1-c1ccc(cc1)-c1cc(C(O)=O)c2n(C)nnc2c1. References: Gabrielle McDonald, et al. Selective...
| Application: | DHODH inhibitor |
| CAS | 1623416-31-8 |
| MW: | 343.38 D |
From 67.00€
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DHODH Protein, Human, Recombinant (His)
Item number: TGM-TMPH-01225-100ug
Description: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
| Keywords: | Dihydroorotate dehydrogenase (quinone), mitochondrial, DHODH, Dihydroorotate oxidase, DHOdehase |
| MW: | 45.1 kD |
From 198.00€
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Leflunomide-d4
Item number: TGM-TMID-0237-1mg
Description: Leflunomide-d4 is a deuterated compound of Leflunomide. Leflunomide has a CAS number of 75706-12-6. Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. Smiles: C(NC1=C(C(=C(C(F)(F)F)C(=C1[2H])[2H])[2H])[2H])(=O)C2=C(C)ON=C2
| Application: | GC-MS, LC-MS, quantification, internal standard, dihydroorotate dehydrogenase inhibitor |
| CAS | 1189987-23-2 |
| MW: | 274.23 D |
Please request pricing for this article.
DHODH Protein, Mouse, Recombinant (E. coli, His)
Item number: TGM-TMPH-02627-100ug
Description: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
| Keywords: | DHODH, Dihydroorotate oxidase, Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase |
| MW: | 45.0 kD |
From 236.00€
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DHODH Protein, Mouse, Recombinant (His)
Item number: TGM-TMPH-02850-100ug
Description: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
| Keywords: | DHOdehase, DHODH, Dihydroorotate oxidase, Dihydroorotate dehydrogenase (quinone), mitochondrial |
| MW: | 44.2 kD |
From 1,982.00€
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DHODH Protein, Rat, Recombinant (His)
Item number: TGM-TMPH-03278-100ug
Description: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
| Keywords: | Dihydroorotate oxidase, Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase, DHODH |
| MW: | 43.5 kD |
From 359.00€
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PTC299
Item number: TGM-T12574-100mg
Description: PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA translation and selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydrolactate...
| Keywords: | Emvododstat, (4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate |
| Application: | Targets vascular endothelial growth factor A (VEGFA) |
| CAS | 1256565-36-2 |
| MW: | 467.34 D |
From 119.00€
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