39 products were found matching "K00207"!

Description: 5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil. Target: Endogenous Metabolite. Smiles: O=C1NC(=O)NCC1. References: Sreekumar A, et al.Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.Nature. 2009 Feb 12,457(7231):910-4. doi:...

Description: Eniluracil (GW776C85) is an orally activedihydropyrimidine dehydrogenase (DPD) inhibitor,increases the oral bioavailability of 5-FU to 100%, facilitating uniform absorption and predictable toxicity. Target: Others. Smiles: O=c1[nH]cc(C#C)c(=O)[nH]1. References: Kindler H L , Schilsky R L . Eniluracil:...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Eniluracil is an irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD, Ki = 1.6 µM), the rate-determining enzyme in the catabolism of pyrimidines, including 5-fluorouracil (Cay-14416). It inhibits liver DPD and elevates plasma pyrimidine levels in rats (ED50s = 1.8 and 10 µg/kg, respectively). Eniluracil...

5,6-Dihydrouracil is a catabolite of uracil (Cay-26088). It is formed from uracil by dihydropyrimidine dehydrogenase. The plasma ratio of 5,6-dihydrouracil to uracil has been used as a phenotypic marker of dihydropyrimidine dehydrogenase activity.Formal Name: dihydro-2,4(1H,3H)-pyrimidinedione. CAS Number: 504-07-4....

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Dihydropyrimidine Dehydrogenase, also called DPD, is an enzyme that in humans is encoded by the DPYD gene. The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. DPYD (Dihydropyrimidine Dehydrogenase), also called DPD, is an enzyme that in humans is encoded by the DPYD gene. The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine...

Protein function: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil. [The UniProt Consortium]

White powder. Soluble in methanol. Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the...