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Ethyl Mycophenolate
Item number: Cay35065-25
Ethyl mycophenolate is a potential impurity found in commercial preparations of the mycophenolic acid prodrug mycophenolate mofetil.Formal Name: (4E)-6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid, ethyl ester. CAS Number: 32483-51-5. Molecular Formula: C19H24O6....
| Keywords: | (4E)-6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid, ethyl ester |
| Application: | Potential impurity found in commercial mycophenolate mofetil preparations |
| CAS | 32483-51-5 |
| MW: | 348.4 D |
From 69.00€
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AVN-944
Item number: TGM-T1979-100mg
Description: AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2. Target: Dehydrogenase. Smiles: CC[C@H](CC#N)OC(=O)N[C@@H](C)c1cccc(NC(=O)Nc2ccc(-c3cnco3)c(OC)c2)c1. References: Zimmermann AG, et al. Prog Nucleic Acid Res Mol Biol. 1998,61:181-209.
| Keywords: | VX-944 |
| Application: | IMPDH inhibitor |
| CAS | 297730-17-7 |
| MW: | 477.51 D |
From 55.00€
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Mycophenolic acid-beta-D-glucuronide
Item number: TGM-T60104-10mg
Description: Mycophenolic acid glucuronide is the glucuronide metabolite of mycophenolic acid in human plasma. Target: Others. Smiles: COc1c(C)c2COC(=O)c2c(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)c1C\C=C(/C)CCC(O)=O. References: Shipkova M, Niedmann PD, Armstrong VW, Schütz E, Wieland E, Shaw LM, Oellerich...
| Application: | Mycophenolic acid metabolite, internal standard |
| CAS | 31528-44-6 |
| MW: | 496.46 D |
From 88.00€
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Mycophenolate Mofetil
Item number: TGM-T6293-100mg
Description: Mycophenolate Mofetil (TM-MMF), an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH). Target: Dehydrogenase, Apoptosis, Drug Metabolite. Smiles: COC1=C(C)C2=C(C(=O)OC2)C(O)=C1C\C=C(/C)CCC(=O)OCCN1CCOCC1....
| Keywords: | RS 61443, TM-MMF |
| Application: | Targets IMP dehydrogenase [EC:1.1.1.205] (IMPDH, guaB) |
| CAS | 128794-94-5 |
| MW: | 433.49 D |
From 46.00€
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Mizoribine
Item number: TGM-T1188-100mg
Description: Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis. Target: SARS-CoV, Tyrosinase, HCV Protease. Smiles: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(O)=C(C(N)=O)N=C2. References: Turka LA, et al. J Clin...
| Keywords: | Bredinin, HE 69, NSC 289637 |
| Application: | Targets IMP dehydrogenase [EC:1.1.1.205] (IMPDH, guaB) |
| CAS | 50924-49-7 |
| MW: | 259.22 D |
From 45.00€
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Mycophenolic acid
Item number: TGM-T1335-100mg
Description: Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity. Target: Dehydrogenase, Antibacterial, Apoptosis, UGT, Antifungal, Antibiotic, Endogenous Metabolite. Smiles: CC1=C2C(=C(O)C(C/C=C(/CCC(O)=O)\C)=C1OC)C(=O)OC2. References:...
| Keywords: | Mycophenolate, RS-61443 |
| Application: | Targets IMP dehydrogenase [EC:1.1.1.205] (IMPDH, guaB) |
| CAS | 24280-93-1 |
| MW: | 320.34 D |
From 42.00€
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Merimepodib
Item number: TGM-T3444-100mg
Description: Merimepodib (VX-497) is a novel, noncompetitive inhibitor of inosine monophosphate dehydrogenase (IMPDH). Target: HBV, HCV Protease, Antiviral, Dehydrogenase. Smiles: COc1cc(NC(=O)Nc2cccc(CNC(=O)O[C@H]3CCOC3)c2)ccc1-c1cnco1. References: Jain J, et al. VX-497: a novel, selective IMPDH inhibitor and...
| Keywords: | VX-497, VI-21497 |
| Application: | Targets IMP dehydrogenase [EC:1.1.1.205] (IMPDH, guaB) |
| CAS | 198821-22-6 |
| MW: | 452.46 D |
From 40.00€
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Ribavirin 5'-monophosphate (lithium salt)
Item number: TGM-T37877-1mg
Description: Ribavirin 5'-monophosphate (lithium salt) directly inhibits IMP dehydrogenase (converts IMP to XMP). Target: Others. Smiles: [Li].NC(=O)c1ncn(n1)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O
| Application: | Antiviral, IMPDH inhibitor |
| CAS | 66983-94-6 |
| MW: | 331.13 D |
From 142.00€
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Tiazofurin
Item number: TGM-T40686-100mg
Description: Tiazofurin (NSC-286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent IMP dehydrogenase (IMPDH) inhibitor. Target: Dehydrogenase. Smiles:...
| Keywords: | NSC 286193, Riboxamide |
| Application: | Targets IMP dehydrogenase [EC:1.1.1.205] (IMPDH, guaB) |
| CAS | 60084-10-8 |
| MW: | 260.27 D |
From 152.00€
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Mycophenolic acid sodium
Item number: TGM-T61099-100mg
Description: Mycophenolic acid sodium is a potent uncompetitive inhibitor of inosine monophosphate dehydrogenase (IMPDH) with an EC50 of 0.24 µM, exhibiting broad antiviral activity against RNA viruses, including influenza, along with immunosuppressive properties and antiangiogenic and antitumor effects [1][2]....
| Application: | Targets IMP dehydrogenase [EC:1.1.1.205] (IMPDH, guaB) |
| CAS | 37415-62-6 |
| MW: | 342.323 D |
From 2,142.00€
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Xanthosine 5'-monophosphate sodium salt
Item number: TGM-T8186-20mg
Description: Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) serves as an intermediate in purine metabolism. Target: Others. Smiles: [Na+].[Na+].O[C@@H]1[C@@H](COP([O-])([O-])=O)O[C@H]([C@@H]1O)n1cnc2c1[nH]c(=O)[nH]c2=O. References: Noguchi Y , Shimba N , Kawahara Y , et al. 31P NMR studies of energy...
| Keywords: | L-XMP Sodium, XMP |
| Application: | IMP dehydrogenase (IMPDH) metabolite |
| CAS | 25899-70-1 |
| MW: | 408.17 D |
57.00€
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Mycophenolate Mofetil-d4
Item number: TGM-TMID-0086-1mg
Description: Mycophenolate Mofetil-d4 is a deuterated compound of Mycophenolate Mofetil. Mycophenolate Mofetil has a CAS number of 128794-94-5. Mycophenolate mofetil, an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase...
| Application: | GC-MS, LC-MS, internal standard |
| CAS | 1132748-21-0 |
| MW: | 437.52 D |
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