67 products were found matching "K00036"!

Description: G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production. Target: Dehydrogenase. Smiles: O=C1CCCCc2nc(Nc3csc(c3)C#N)ncc12. References: Ghergurovich J M , Juan C. García-Caaveras, Wang J , et al. A small molecule G6PD inhibitor reveals immune dependence on...

Description: Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate...

Organism: Escherichia coli (strain K12). Source: E.coli. Expression Region: 1-486aa. Protein Length: Partial. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MAVTQTAQAC DLVIFGAKGD LARRKLLPSL YQLEKAGQLN PDTRIIGVGR ADWDKAAYTK VVREALETFM KETIDEGLWD TLSARLDFCN LDVNDTAAFS RLGAMLDQKN RITINYFAMP PSTFGAICKG...

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The G6PD gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in...

G6PD activator AG1 is an activator of glucose-6-phosphate dehydrogenase (G6PDH, EC50 = 3.4 µM for G6PDHR459L). It selectively induces the dimerization of G6PDHR459L over 6-phosphogluconate dehydrogenase (6PGD), GAPDH, aldehyde dehydrogenase 2 (ALDH2), and ALDH3A1. G6PD activator AG1 decreases the levels of reactive...

Glucose-6-phosphate dehydrogenase (G6PDH) is a cytosolic enzyme that catalyzes the first step in the pentose phosphate pathway. This pathway includes converting glucose to ribose-5-phosphate, a precursor to RNA, DNA, ATP, CoA, NAD, and FAD. The pathway also generates NADPH. G6PDH deficiency, the most common enzyme...

Glucose-6-phosphate dehydrogenase (G6PDH, EC 1.1.1.49) is purified from a recombinant E. coli strain. G6PDH is a cytosolic enzyme that converts glucose-6-phosphate into 6-phosphoglucono-delta-lactone, the rate-limiting step of the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells...

G6PDi-1 is a reversible and noncompetitive inhibitor of glucose-6-phosphate dehydrogenase (G6PDH, IC50 = 0.07 µM), the enzyme that converts G6P to 6-phosphogluconolactone using NADP+ as a cofactor in the first step of the pentose phosphate pathway. G6PDi-1 (10 and 50 µM) reduces NADPH levels in a variety of cultured...

A broad-spectrum cancer chemopreventive agent. A potent inhibitor of glucose-6- phosphate dehydrogenase.

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human G6PD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human G6PD. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat G6PD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat G6PD. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse G6PD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse G6PD. Next,...