- Search results for Immune Modulators
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9 products were found matching "Immune Modulators"!
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Item number: Cay10006292-50
Fingolimod is an immune modulator, a prodrug form of the sphingosine-1-phosphate (S1P) receptor agonist FTY720 phosphate (Cay-10008639), and a derivative of myriocin (Cay-63150). It selectively inhibits calcium-dependent cytosolic phospholipase A2 (cPLA2) over calcium-independent PLA2 (iPLA2) and secretory PLA2...
Keywords: | FTY720, 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, hydrochloride |
Application: | Immune Modulator |
CAS | 162359-56-0 |
MW: | 343.9 D |
From 84.00€
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Item number: 600-401-CQ9
Anti-MARCH8 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with MARCH8 from other sources has not been determined. Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and...
Keywords: | Anti-MIR, Anti-c-MIR, Anti-MARCH8, EC=6.3.2.-, Anti-MARCH-VIII, Anti-RING finger protein 178, Anti-E3 ubiquitin-protein... |
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
684.00€
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Item number: ATA-HPA014597.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS. [The UniProt...
Keywords: | Anti-c-MIR, Anti-MARCH8, Anti-MARCH-VIII, EC=2.3.2.27, Anti-RING finger protein 178, Anti-E3 ubiquitin-protein ligase... |
Application: | WB, IHC |
Host: | Rabbit |
Species reactivity: | human |
From 335.00€
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Item number: Cay16841-1
FTY720 is an immune modulator that down-regulates sphingosine-1-phosphate (S1P) receptors, enhances the activity of the sphingosine transporter Abcb1 and the leukotriene C4 transporter Abcc1, and inhibits cytosolic phospholipase A2 activity. It is known that some of the effects of FTY720 require its phosphorylation...
Keywords: | N-[2R-hydroxy-1R-(hydroxymethyl)-3E-heptadecenyl]-2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol,monohydrochloride |
Application: | Immune modulator |
CAS | 2319882-09-0 |
MW: | 510 D |
From 44.00€
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Item number: ELK-ES9629.100
MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane...
Keywords: | Anti-c-MIR, Anti-MARCH8, Anti-MARCH-VIII, Anti-RING finger protein 178, Anti-E3 ubiquitin-protein ligase MARCHF8,... |
Application: | WB, ELISA |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, |
From 169.00€
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Item number: ATA-APrEST72948.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS. [The UniProt...
Keywords: | c-MIR, MARCH8, MARCH-VIII, EC=2.3.2.27, RING finger protein 178, E3 ubiquitin-protein ligase MARCHF8, Cellular modulator... |
Application: | Control antigen |
Expressed in: | E.coli |
Origin: | human |
247.00€
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Item number: G-CAB12962.20
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS. [The UniProt...
Keywords: | Anti-c-MIR, Anti-MARCH8, Anti-MARCH-VIII, EC=2.3.2.27, Anti-RING finger protein 178, Anti-E3 ubiquitin-protein ligase... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
149.00€
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Item number: IAX-200-056-M001
In recent years several groups have studied the sequence requirements, specificity, signaling pathways and kinetics of the TLR (Toll-like receptor) 9 suppression by inhibitory oligonucleotide motifs, which led to a class of novel inhibitory oligonucleotide (iODNs), that is independent of the previously thought...
Keywords: | Inhibitory ODN (iODN): Class I/III, ODN immunoregulatory sequence 661 (IRS661) |
Application: | Immune modulator |
MW: | 6761 D |
From 179.00€
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Item number: IAX-200-208-M001
Unmethylated CG dinucleotides within particular sequence contexts are responsible for the immunostimulatory activity of bacterial DNA. Synthetic oligonucleotides (ODN) that contain such CpG motifs (CpG ODNs) mimic microbial DNA. The innate immune system of vertebrates has the ability to recognize CpG motifs in...
Keywords: | CTRL ODN 2, Negative Control for inhibitory ODNs (iODNs) and CpG ODNs (TLR9 agonists) |
Application: | Immune modulator |
Species reactivity: | human, mouse, rat |
MW: | 7324 D |
From 179.00€
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