Glutathione reductase (EC 1.8.1.7) is a ubiquitous homodimeric enzyme with molecular weights ranging from 100 kDa, for the human erythrocyte enzyme, to 118 kDa, for the yeast enzyme. It contains one FAD per protein subunit and shows Km values of 4-9 µM for NADPH and of 55-65 µM for oxidized glutathione. The GR is...

gor, also known as Glutathione reductase, belongs to the class-I pyridine nucleotide disulfide oxidoreductase family. The main function of the protein is to maintain high levels of reduced glutathione in the cytosol. With the concomitant oxidation of NADPH, Glutathione reductase transforms oxidized glutathione to...