19 products were found matching "GeneID 12362"!

Caspase-1, also known as interleukin-1-beta (IL-1beta) -converting enzyme (ICE), is a member of the cysteine-aspartic protease (caspase) family . The caspase family are aspartic proteolytic enzymes that play a key role in apoptotic cell death and inflammation. Protein function: Thiol protease involved in a variety...

Detects mouse Caspase-1 (p10 and p20 domain). Does not detect human Caspase-1. Contains sufficient materials to run ELISAs on 5 x 96-well plates. Sensitivity: 100 pg/ml. Contains standard protein, coating and detection antibodies and Streptavidin-HRP.

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CASP1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CASP1. Next,...

Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4...

Protein function: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis....

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase-1 is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta, IL-18, and IL-33 precursor proteins. It belongs to a family of cysteine proteases known as caspases that always cleave...

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of CASP1 in serum, plasma and other biological fluids. Detection Range: 31.25--2000pg/mL. Sensitivity: 18.75pg/mL. Protein function: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is...

ELISA Type: Sandwich. Sensitivity: 18.75pg/mL. Range: 31.25--2000pg/mL. Protein function: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol...

Activity: Testing in progress Protein Construction: A DNA sequence encoding the Mouse CASP1 protein (P29452) (Asn 120-Asp 296) was expressed with a N-His tag. Sequence: Asn 120-Asp 296. Fusion tag: N-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 21 kDa. Protein function: Caspase-1,...

Protein function: Thiol protease involved in a variety of inflammatory processes by proteolytically cleaving other proteins, such as the precursors of the inflammatory cytokines interleukin-1 beta (IL1B) and interleukin 18 (IL18) as well as the pyroptosis inducer Gasdermin-D (GSDMD), into active mature peptides...

Thiol protease involved in a variety of inflammatory processes by proteolytically cleaving other proteins, such as the precursors of the inflammatory cytokines interleukin-1 beta (IL1B and interleukin 18 (IL18 as well as the pyroptosis inducer Gasdermin-D (GSDMD, into active mature peptides. Plays a key role in cell...