- Search results for Cay10245-50
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13 products were found matching "Cay10245-50"!
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Item number: Cay21045-500
NADP+ is the oxidized form of the electron donor nicotinamide adenine dinucleotide phosphate (NADPH, Cay-9000743). It serves as a cofactor in various biological reactions. In addition, the balance between these reduced and oxidized forms plays key roles in diverse cellular functions, including cell survival, the...
Keywords: | Coenzyme II, Nicotinamide adenine dinucleotide phosphate, TPN, beta-NADP, adenosine 5'-(trihydrogen diphosphate),... |
Application: | Cofactor |
MW: | 743.4 D |
From 46.00€
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Item number: Cay41245-500
LSN3318839 is a positive allosteric modulator (PAM) of glucagon-like peptide 1 receptor (GLP-1R). It potentiates increases in cAMP accumulation induced by the GLP-1R full agonist GLP-1 (9-36), but not the GLP-1R partial agonist GLP-1 (7-36), in INS-1 832/3 cells. LSN3318839 (1 and 3 µM) increases insulin levels in...
Keywords: | 2-[1-[(1R)-1-(2,6-dichloro-3-cyclopropylphenyl)ethyl]-1H-imidazo[4,5-c]pyridin-6-yl]-alphaR-methyl-benzeneacetic acid |
Application: | Positive allosteric GLP-1R modulator |
CAS | 2764704-18-7 |
MW: | 480.4 D |
From 180.00€
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Item number: Cay24550-500
Neuropeptide S is a neuropeptide expressed in the brain, primarily in glutamatergic neurons near the locus coeruleus and in the trigeminal sensory nucleus, as well as in neurons of the lateral parabrachial nucleus in rat brain. It is an agonist of the neuropeptide S receptor (NPSR) with an EC50 value of 9.4 nM for...
Keywords: | NPS,... |
Application: | NPSR agonist, neuropeptide |
Origin: | human |
MW: | 2187.5 D |
From 187.00€
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Item number: Cay10240-1
PCSK9 is a member of the subtilisin serine protease family with an important role in low-density lipoprotein (LDL) metabolism. Mutation in the PCSK9 gene is associated with autosomal dominant hypercholesterolemia which is characterized by an increase in LDL cholesterol levels. PCSK9 overexpression in wild-type mice...
Keywords: | Anti-PC9, Anti-PC9, Anti-PCSK9, Anti-NARC1, Anti-NARC-1, Anti-NARC-1, Anti-PSEC0052, Anti-Proprotein convertase 9,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
456.00€
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Item number: Cay10550-500
4-biphenylthio Carboxamide is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: [1,1'-biphenyl]-4-carbothioamide. CAS Number: 13363-50-3. Synonyms: Biphenyl-4-Carbothioic Acid amide. Molecular Formula: C13H11NS. Formula Weight: 213.3. Purity: >98%. Formulation: (Request formulation change), A...
Keywords: | Biphenyl-4-Carbothioic Acid amide, [1,1'-biphenyl]-4-carbothioamide |
Application: | Chemical synthesis, Building block |
CAS | 13363-50-3 |
MW: | 213.3 D |
From 48.00€
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Item number: Cay14250-50
Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 µM, IC50 = 1.2 µM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation...
Keywords: | ICI 176334, ZD 176334, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-propanamide |
Application: | Androgen receptor antagonist, Metabolic studies |
CAS | 90357-06-5 |
MW: | 430.4 D |
From 43.00€
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Item number: Cay9001245-50
Docosahexaenoic acid ethyl ester-d5 (DHA ethyl ester-d5) is intended for use as an internal standard for the quantification of docosahexaenoic acid ethyl ester (Cay-9090310) by GC- or LC-MS. DHA ethyl ester is an esterified form of the omega-3 fatty acid DHA (Cay-90310, Cay-17950). DHA ethyl ester increases plasma...
Keywords: | Cervonic Acid ethyl ester-d5, DHA ethyl ester-d5, 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid, ethyl ester-d5 |
Application: | GC-MS, LC-MS, internal standard |
MW: | 361.6 D |
From 84.00€
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Item number: Cay10250-1
Programmed cell death protein 4 (PDCD4) levels are elevated during apoptosis and absent in many cancer samples. Loss of PDCD4 expression is an important event in cancer cell progression whereas the restoration of PDCD4 protein can lower metalloproteinase activity and possible metastasis. The known isoforms of PDCD4...
Keywords: | Anti-H731, Anti-PDCD4, Anti-Protein 197/15a, Anti-Protein 197/15a, Anti-Nuclear antigen H731-like, Anti-Nuclear antigen... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay41025-50
N-desmethyl Enzalutamide is an active metabolite of the androgen receptor antagonist enzalutamide (Cay-11596). It is formed from enzalutamide by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8.Formal Name: 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-benzamide....
Keywords: | N-desmethyl MDV 3100,... |
Application: | Enzalutamide (androgen receptor antagonist) active metabolite |
CAS | 1242137-16-1 |
MW: | 450.4 D |
From 119.00€
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Item number: Cay90245-50
Stearoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called anandamides. Stearoyl ethanolamide is the most abundant of several fatty acid ethanolamides produced by the PLD hydrolysis of mouse neuroblastoma cell membrane phospholipids. The specific role of stearoyl ethanolamide...
Keywords: | Ceramid, Stearic Acid Ethanolamide, N-(2-hydroxyethyl)-octadecanamide |
Application: | Bioactive lipid assays |
CAS | 111-57-9 |
MW: | 327.6 D |
From 84.00€
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Item number: Cay14550-1
5-fluoro PB-22 is a synthetic cannabinoid that is an analog of potent 5-fluoropentyl JWH-type cannabimimetics. 5-fluoro PB-22 5-hydroxyisoquinoline isomer differs from 5-fluoro PB-22 by having the quinoline group replaced with an isoquinoline group attached at its five position. The physiological and pharmacological...
Keywords: | 1-(5-fluoropentyl)-1H-indole-3-carboxylic acid, 5-isoquinolinyl ester |
Application: | Analytical reference standard, synthetic cannabinoid analog |
CAS | 2365471-16-3 |
MW: | 376.4 D |
From 109.00€
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Item number: Cay10010740-1
Cellular prion protein (PrPc) is a cell surface glycoprotein expressed in brain, spinal cord, and several peripheral tissues that if mutated to the protease-resistant isoform PrPSc (scrapie PrP, PrPres) can result in one of several fatal neurodegenerative diseases. Prion diseases, including mad cow disease (bovine...
Keywords: | 3-(4-Nitrophenyl)-1-phenyl-2-pyrazolin-5-one, 2,4-dihydro-5-(4-nitrophenyl)-2-phenyl-3H-pyrazol-3-one |
Application: | PrPc accumulation inhibitor |
CAS | 34320-83-7 |
MW: | 281.3 D |
From 38.00€
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