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Item number: Cay31736-100

1,3-Di-o-tolylguanidine (DTG) is a sigma (sigma) receptor ligand (Kis = 61 and 42 nM for sigma1 and sigma2 receptors, respectively). In vivo, DTG (10, 15, and 20 mg/kg, i.p.) increases latency to tail withdrawal in the tail flick test and induces hypothermia in mice. It decreases infarct size and increases the...

Keywords:	DTG, NSC 132023, NSC 473, N,N'-bis(2-methylphenyl)-guanidine
Application:	sigma receptor ligand
CAS	97-39-2
MW:	239.3 D

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