Description: Isoliquiritigenin (ISL) is a flavonoid natural product that inhibits influenza virus replication (EC50=24.7 µM) and aldose reductase activity (IC50=320 nM). Isoliquiritigenin has antitumor activity. Target: Autophagy, Reductase, Apoptosis, Influenza Virus. Smiles:...

Isoliquiritigenin is a flavonoid that is found in Glycyrrhizae species and has diverse biological activities including anticancer, anti-steatotic, antioxidant, anti-inflammatory, gastroprotective, and estrogenic properties. It reduces tumor growth in an NCI-H1975 non-small cell lung cancer (NSCLC) mouse xenograft...

Yellow solid. Soluble in DMSO, methanol or ethanol. Anticancer. Apoptosis inducer and cell proliferation inhibitor. Autophagy inducer, Anti-angiogenic. VEGF/VEGFR-2 signaling inhibitor, Antioxidant and antibacterial, AMPK-mediated GSK3beta inhibitor, Anti-inflammatory. Inhibits translocation and activation of...

A natural flavonoid present in licorice, shallot and bean sprouts. Known to induce cell cycle arrest and apoptosis of various cancer cells. Dual inhibitor of histone deacetylase (HDAC) enzymes and NF-KB. Also prevents 6-hydroxydopamine-induced apoptosis in dopaminergic neurons.