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N-Desethylamiodarone (hydrochloride)
N-Desethylamiodarone (hydrochloride)

Item number: Cay9000537-10

Amiodarone (Cay-15213) is a class III antiarrhythmic agent, in that it prolongs both cardiac action potential and refractoriness by blocking potassium currents. It inhibits the voltage-gated potassium channel hERG, also known as KCNH2, with an IC50 value of 1 µM. In humans, cytochrome P450 3A is involved in the...
Keywords: (2-butyl-3-benzofuranyl)[4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl]-methanone, monohydrochloride
Application: Antiarrhythmic agent
CAS 96027-74-6
MW: 653.7 D
From 81.00€ *
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Desethylamiodarone hydrochloride
Desethylamiodarone hydrochloride

Item number: TGM-T11002-100mg

Description: Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride), formed by the CYP3A isozyme, is the main active metabolite of amiodarone, an antiarrhythmic drug that inhibits ATP-sensitive potassium channels with an IC50 of 19.1 µM. Target: Others. Smiles:...
Keywords: LB 33020 hydrochloride, N-desethylamiodarone hydrochloride
CAS 96027-74-6
MW: 653.72 D
From 198.00€ *
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