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4-(2,2,3-Trimethylcyclopentyl)butanoic Acid

Item number: Cay19606-1

4-(2,2,3-Trimethylcyclopentyl)butanoic acid is an orthosteric, insurmountable antagonist of the human bitter taste receptors hTAS2R31 and hTAS2R43. It prevents the activation of hTAS2R31 by saccharin and acesulfame K in cells with IC50 values of 7.9 and 2.4 µM, respectively. In human sensory trials,...

Keywords:	GIV3727, 2,2,3-trimethyl-cyclopentanebutanoic acid
Application:	hTAS2R31 / hTAS2R43 antagonist
CAS	957136-80-0
MW:	198.3 D

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