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Item number: Cay10444-10

PCI 34051 is a potent histone deacetylase (HDAC) 8 inhibitor (IC50 = 0.01 µM) with >200-fold selectivity over HDAC isoforms 1, 2, 3, 6, and 10 (IC50s = 4, >50, >50, 2.9, and 13 µM, respectively). PCI 34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias (GI50s = 2.4 - 4...

Keywords:	N-hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide
Application:	HDAC inhibitor
CAS	950762-95-5
MW:	296.3 D

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