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B-Raf IN 1
B-Raf IN 1

Item number: TGM-T1845-100mg

Description: B-Raf IN 1 is an inhibitor of B-Raf (IC50: 24 nM) and c-Raf (IC50: 25 nM). Target: Raf. Smiles: CN(C)Cc1ccc(cc1)-c1cnn2c(ccnc12)-c1cccc(NC(=O)c2cccc(c2)C(F)(F)F)c1. References: Berger DM, et al. Bioorg Med Chem Lett. 2009 Dec 1,19(23):6519-23.
Application: BRAF / RAF1 inhibitor
CAS 950736-05-7
MW: 515.53 D
From 83.00€ *
Review
B-RAF IN 1
B-RAF IN 1

Item number: Cay23434-1

B-RAF IN 1 is an inhibitor of B-RAF (IC50 = 24 nM) that also inhibits C-RAF (IC50 = 25 nM). It is selective over 13 other kinases, including PKCalpha, IKKbeta, and PI3Kalpha, at concentrations greater than 2 µM, but does inhibit p38alpha and CAMKII (IC50s = 216 and 822 nM, respectively). B-RAF IN 1 binds to B-RAF in...
Keywords: B-RAF Inhibitor 1,...
Application: BRAF / RAF1 inhibitor
CAS 950736-05-7
MW: 515.5 D
From 85.00€ *
Review
B-Raf IN 1
B-Raf IN 1

Item number: LKT-B6902.1

B-Raf and c-Raf inhibitor.
Application: B-Raf and c-Raf inhibitor
CAS 950736-05-7
MW: 515.54 D
From 281.00€ *
Review