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Item number: Cay22954-5

Peficitinib is an inhibitor of JAK (IC50s = 3.9, 5, and 0.71 nM for JAK1-3, respectively). It is 14-fold selective for JAK1 and JAK3 over JAK2 in erythropoietin-induced leukemia cell proliferation assays. Peficitinib inhibits IL-2-induced proliferation of rat splenocytes (IC50 = 10 nM) and phosphorylation of STAT5...

Keywords:	ASP015K, JNJ-54781532, 4-[(5-hydroxytricyclo[3.3.1.13,7]dec-2-yl)amino]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide, stereoisomer
Application:	JAK1 / JAK2 / JAK3 / TYK2 inhibitor
CAS	944118-01-8
MW:	326.4 D

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