4 products were found matching "941678-49-5"!
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Ruxolitinib
Item number: Cay11609-1
Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. A JAK2 gene fusion mutation, JAK2V617F, that causes unchecked activation of various growth factors and cytokines, has been linked to myeloproliferative...
| Keywords: | INCB 018424, betaR-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile |
| Application: | Jak1/2 inhibitor |
| CAS | 941678-49-5 |
| MW: | 306.4 D |
From 34.00€
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Ruxolitinib
Item number: AG-CR1-3624-M100
White to off-white solid. Soluble in DMSO or ethanol. Insoluble in water. Antineoplastic, anti-inflammatory and immunomodulating agent, Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50 = 322nM), Affects DC...
| Keywords: | INCB018424, INC 424 |
| Application: | JAK1 inhibitor, JAK2 inhibitor |
| CAS | 941678-49-5 |
| MW: | 306,4 D |
From 72.00€
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Ruxolitinib
Item number: TGM-T1829-100mg
Description: Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis. Target: Mitophagy, Autophagy, Apoptosis, Tyrosine Kinases, JAK. Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12....
| Keywords: | INCB018424, (R)-Ruxolitinib |
| Application: | Targets Janus kinase 1 [EC:2.7.10.2] (JAK1) |
| CAS | 941678-49-5 |
| MW: | 306.36 D |
From 54.00€
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INCB018424
Item number: LKT-I5210.5
JAK1/2 inhibitor.
| Keywords: | Ruxolitinib |
| Application: | Janus kinase 1 (JAK1) inhibitor, janus kinase 2 (JAK2) inhibitor |
| CAS | 941678-49-5 |
| MW: | 306.37 D |
From 136.00€
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