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NVP-BHG712
Item number: TGM-T6348-100mg
Description: NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition, also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 µM, 1.266 µM and 1.667 µM, respectively. Target: Ephrin Receptor, Bcr-Abl, Src, Raf. Smiles:...
| Application: | EphB4 kinase autophosphorylation inhibitor |
| CAS | 940310-85-0 |
| MW: | 503.48 D |
From 31.00€
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NVP-BHG712
Item number: Cay18489-5
The EphB4 receptor tyrosine kinase (cloned from erythropoietin-producing hepatocellular carcinoma) and its ligand ephrinB2 play an important role in embryonic vessel development and vascular remodeling. Signaling from this pair is also involved in tumor angiogenesis. NVP-BHG712 is an orally bioavailable inhibitor of...
| Keywords: | 4-methyl-3-[[1-methyl-6-(3-pyridinyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino]-N-[3-(trifluoromethyl)phenyl]-benzamide |
| Application: | EphB4 kinase autophosphorylation inhibitor |
| CAS | 940310-85-0 |
| MW: | 503.5 D |
From 52.00€
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NVP-BHG712
Item number: LKT-N8460.1
NVP-BHG712 is a specific inhibitor of c-Raf, c-Src and c-Abl
| Keywords: | 4-methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide - |
| Application: | c-Raf / c-SRC / c-Abl inhibitor |
| CAS | 940310-85-0 |
| MW: | 503.48 D |
From 98.00€
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