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Fluvastatin
Item number: TGM-T21405-100mg
Description: Fluvastatin (XU-62320) is a potent and competitive HMG-CoA reductase inhibitor (IC50: 8 nM) that inhibits oxidative stress in vascular smooth muscle cells through an Nrf2-dependent pathway, and is used for the reduction of plasma cholesterol levels and the prevention of cardiovascular disease. Target:...
| Keywords: | Lescol, Cranoc, Vastin, XU-62320, Canef |
| CAS | 93957-54-1 |
| MW: | 411.47 D |
From 31.00€
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Fluvastatin
Item number: Cay10010334-10
Fluvastatin is an inhibitor of HMG-CoA reductase (Ki = 0.3 nM for the rat enzyme). It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin inhibits oxidized LDL-induced ferroptosis and reverses oxidized LDL-induced decreases in glutathione peroxidase 4 (GPX4) and system Xc-...
| Keywords: | 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid |
| Application: | HMG-CoA reductase inhibitor |
| CAS | 93957-54-1 |
| MW: | 411.5 D |
From 54.00€
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