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Item number: Cay41595-10

JC2-11 is an inflammasome inhibitor. It inhibits increases in IL-1beta production induced by the NOD-like receptor protein 3 (NLRP3) activators ATP (Cay-14498, Cay-40182), nigericin (Cay-11437), or monosodium urate crystals in LPS-primed primary mouse bone marrow-derived macrophages (BMDMs) when used at...

Keywords:	1-(3-fluoro-4-methoxyphenyl)-3-(4-hydroxy-3-2-propen-1-one
Application:	Inflammasome inhibitor
CAS	937820-89-8
MW:	302.3 D

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JC2-11

Item number: TGM-T77579-100mg

Description: JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen species (ROS) production and caspase-1 activity.JC2-11 reduces caspase-1 (p20)...

CAS	937820-89-8
MW:	302.3 D

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