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GSK-690693
Item number: TGM-T6285-100mg
Description: GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1. Target: PKC, Serine Protease, AMPK, Autophagy, Akt. Smiles: CCn1c(nc2c(ncc(OC[C@H]3CCCNC3)c12)C#CC(C)(C)O)-c1nonc1N. References: Rhodes N,...
| Keywords: | GSK690693 |
| Application: | pan-Akt inhibitor |
| CAS | 937174-76-0 |
| MW: | 425.48 D |
From 42.00€
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GSK690693
Item number: Cay16891-1
GSK690693 is an ATP-competitive, pan-Akt kinase inhibitor with IC50 values of 2, 13, and 9 nM for Akt1, 2, and 3, respectively. It also inhibits other members of the AGC kinase family, including AMPK, DAPK3, PAKs, PKA, PKC, PKG, and PrkX (IC50 values range from 2-81 nM). By preventing the phosphorylation of...
| Keywords: | 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-... |
| Application: | Akt kinase inhibitor |
| CAS | 937174-76-0 |
| MW: | 425.5 D |
From 67.00€
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GSK690693
Item number: AG-CR1-3628-M005
Off-white to pale yellow solid. Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. pan-Akt inhibitor targeting Akt1, 2, 3 with IC50 values of 2, 13 and 9 nM, respectively, Inhibits AMPK, DAPK3, PAK4, 5 and 6, as well as members of the AGC kinase family including PKA, PrkX and PKC isoforms (IC50 <, 100 nM),...
| Keywords: | GSK-690693 |
| Application: | pan-Akt inhibitor |
| CAS | 937174-76-0 |
| MW: | 425,5 D |
From 105.00€
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GSK-690693
Item number: LKT-G7242.1
Akt inhibitor.
| Application: | Akt inhibitor |
| CAS | 937174-76-0 |
| MW: | 425.48 D |
From 177.00€
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