3 products were found matching "935666-88-9"!

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AZD-1480
AZD-1480

Item number: TGM-T3069-10mg

Description: AZD1480 is a novel ATP-competitive JAK2 inhibitor (IC50: 0.26 nM), selectivity act against Tyk2 and JAK3, and to a smaller extent against JAK1. AZD1480 has been used in trials studying the treatment of Solid Malignancies, Post-Polycythaemia Vera, Primary Myelofibrosis (PMF), and Essential...
Application: JAK2 inhibitor
CAS 935666-88-9
MW: 348.77 D
From 52.00€ *
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AZD 1480
AZD 1480

Item number: Cay10702-1

Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. Many myeloproliferative diseases have been linked to a mutation in JAK2 where a switch from valine to phenylalanine occurs at the 617 position (V617F). AZD...
Keywords: 5-chloro-N2-[(1S)-1-(5-fluoro-2-pyrimidinyl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine
Application: JAK2 inhibitor
CAS 935666-88-9
MW: 348.8 D
From 50.00€ *
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AZD-1480
AZD-1480

Item number: LKT-A9812.1

JAK1/2 inhibitor.
Keywords: AZD-1480
Application: JAK1/2 inhibitor
CAS 935666-88-9
MW: 348.77 D
From 104.00€ *
Review