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Glimepiride
Glimepiride

Item number: Cay12090-500

Glimepiride is an inhibitor of sulfonylurea receptors (SURs) linked to the inwardly rectifying potassium channel (Kir6.2, IC50s = 3, 5.4, and 7.3 nM for SUR1/Kir6.2, SUR2A/Kir6.2, and SUR2B/Kir6.2, respectively, in Xenopus oocytes expressing the mouse receptor). It also induces intracellular insulin receptor (InsR)...
Keywords: HOE 490,...
Application: Sulfonylurea receptor 1 agonist, ATP-sensitive potassium (KATP) channel inhibitor
CAS 93479-97-1
MW: 490.6 D
From 66.00€ *
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Glimepiride
Glimepiride

Item number: LKT-G4535.1

A sulfonylurea hypoglycemic agent acts with the lowest ratio of insulin release to glucose release when compared with other sulfonylureas. It increases cardiac glucose uptake by enhancing protein expression of glucose transports -1 and -4 independent of insulin responsiveness.
Application: Hypoglycemic agent
CAS 93479-97-1
MW: 490,62 D
From 115.00€ *
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Glimepiride
Glimepiride

Item number: CDX-G0208-G001

Glimepiride is a long-acting sulfonylurea antidiabetic agent inhibiting ATP-sensitive potassium (KATP) channels in pancreatic beta-cells, which leads to the release of insulin. In addition, Glimepiride increases the activity of intracellular insulin receptors. Studies conducted on adipocytes and skeletal muscle...
Keywords: trans-3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-...
Application: Antidiabetic, Hypoglycemic, Sulfonylurea receptor agonist
CAS 93479-97-1
MW: 490.62 D
From 54.00€ *
Review