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BLX3887
BLX3887

Item number: Cay27391-5

BLX3887 is an inhibitor of 15-lipoxygenase type 1 (15-LO-1, IC50 = 32 nM in a cell-free enzyme assay). It is selective for 15-LO-1 over 15-LO-2, which it does not inhibit, 5-LO (IC50 = 472 nM), and 12-LO (IC50 = 3,310 nM). BLX3887 inhibits the production of 15-LO metabolites selectively in eosinophils over...
Keywords: 15-LO-1 Inhibitor 3887, 4,5-dichloro-N-(2-chloro-4-fluorophenyl)-1H-pyrazole-3-carboxamide
Application: 15-LOX-1 (ALOX15) inhibitor
CAS 934758-70-0
MW: 308.5 D
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