3 products were found matching "934660-93-2"!
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Cobimetinib
Item number: TGM-T3623-100mg
Description: Cobimetinib (GDC-0973) is a MEK1 inhibitor (IC50=4.2 nM) with selective and oral activity. Cobimetinib exhibits antitumor activity, inhibiting tumor cell proliferation and inducing apoptosis. Target: Apoptosis, MEK. Smiles: C(=O)(C1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1)N3C[C@](O)(C3)[C@@H]4CCCCN4....
| Keywords: | RG7420, GDC-0973, XL518 |
| Application: | Targets mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] (MAP2K1, MEK1) |
| CAS | 934660-93-2 |
| MW: | 531.31 D |
From 34.00€
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Cobimetinib
Item number: Cay19563-1
Cobimetinib is a potent, orally available inhibitor of MEK1 (IC50 = 4.2 nM). It shows more than 100-fold selectivity for MEK when tested against a panel of more than 100 serine-threonine and tyrosine kinases. Cobimetinib induces differentiation and apoptosis in cancer cell lines and is more effective when combined...
| Keywords: | GDC-0973, RG-7420, XL518,... |
| Application: | Antineoplastic, MEK inhibitor |
| CAS | 934660-93-2 |
| MW: | 531.3 D |
From 66.00€
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GDC-0973
Item number: LKT-G124084.25
MEK1 inhibitor.
| Keywords: | GDC 0973, GDC0973, XL-518, XL 518, XL518, Cobimetinib, RG-7420, RG 7420, RG7420 |
| Application: | Mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase (MEK) inhibitor |
| CAS | 934660-93-2 |
| MW: | 531.32 D |
From 108.00€
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