- Search results for 934240-31-0
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2 products were found matching "934240-31-0"!
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Item number: TGM-T14992-100mg
Description: Raxatrigine hydrochloride is a state-dependent sodium channel blocker and a Nav1.7 sodium channel inhibitor. Target: Others. Smiles: Cl.NC(=O)[C@@H]1CC[C@@H](N1)c1ccc(OCc2ccccc2F)cc1. References: Large CH, et al. The efficacy of sodium channel blockers to prevent phencyclidine-induced cognitive...
Keywords: | CNV1014802 (hydrochloride), GSK-1014802 hydrochloride |
Application: | Targets voltage-gated sodium channel type IX alpha (SCN9A, NAV1.7) |
CAS | 934240-31-0 |
MW: | 350.82 D |
From 86.00€
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Item number: Cay23490-5
Raxatrigine is an inhibitor of voltage-gated sodium channels (Nav, IC50s = 22, 13, 23, 10, 84, 15, 32, and 6 µM for Nav1.1-Nav1.8 channels in a FLIPR membrane potential assay using HEK293 cells). Its activity is state-dependent at the Nav1.7 channel, with a nine-fold increase in potency for the open/inactivated...
Keywords: | GSK1014802A, (2S)-5R-[4-[(2-fluorophenyl)methoxy]phenyl]-2-pyrrolidinecarboxamide, monohydrochloride |
Application: | Voltage-gated sodium channel inhibitor |
CAS | 934240-31-0 |
MW: | 350.8 D |
From 50.00€
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