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FITM
Item number: TGM-T7292-100mg
Description: FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM). Target: GluR. Smiles: CC(C)Nc1cc(ncn1)-c1csc(n1)N(C)C(=O)c1ccc(F)cc1. References: Hayes M , Choudhary V , Ojha N , et al. Fat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid...
| Application: | mGluR1 antagonist |
| CAS | 932737-65-0 |
| MW: | 371.43 D |
From 31.00€
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FITM
Item number: Cay29219-1
FITM is an antagonist of metabotropic glutamate receptor 1 (mGluR1, IC50 = 5.1 nM for the human receptor). It is selective for mGluR1 over mGluR2, mGluR5, and mGluR8 (IC50s = >10, 7, and >10 µM, respectively). FITM (0.3 mg/kg) decreases methamphetamine-induced hyperlocomotion in mice and reverses disruptions in...
| Keywords: | 4-fluoro-N-methyl-N-[4-[6-[(1-methylethyl)amino]-4-pyrimidinyl]-2-thiazolyl]-benzamide |
| Application: | mGluR1 antagonist |
| CAS | 932737-65-0 |
| MW: | 371.4 D |
From 44.00€
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