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Item number: TGM-T14124-100mg

Description: ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 with an IC50 of 1.1 µM and can be used in studies about cartilage destruction in arthritis. Target: Others. Smiles: Cn1nc(c(\C=C2/SC(=S)NC2=O)c1SCc1ccc(Cl)cc1)C(F)(F)F. References: Gilbert AM, et al. 5-((1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one...

Application:	ADAMTS-5 Inhibitor
CAS	929634-33-3
MW:	449.92 D

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ADAMTS-5 Inhibitor

Item number: Cay17188-1

A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) is an aggrecanase in that it cleaves aggrecan, a major proteoglycan in cartilage. While it has key roles in cartilage destruction associated with osteoarthritis, ADAMTS-5 is also involved in other pathways, including neurological processes....

Keywords:	A Disintegrin and Metalloproteinase with Thrombospondin Motifs 5 Inhibitor,...
Application:	Aggrecanase-2 inhibitor
CAS	929634-33-3
MW:	449.9 D

From 78.00€ *

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