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PQ-10
PQ-10

Item number: TGM-T24656-100mg

Description: PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker. Target: PDE. Smiles: COc1cc2ncnc(N3CCC(C3)Oc3cnc4ccccc4n3)c2cc1OC. References: Attia HN, Maklad YA. Neuroprotective effects of coenzyme Q10 on paraquat-induced...
Keywords: A 844337, A-844337, PQ 10, A844337
Application: PDE10 inhibitor
CAS 927691-21-2
MW: 403.43 D
From 38.00€ *
Review
PQ-10
PQ-10

Item number: Cay21867-1

PQ-10 is a potent and selective inhibitor of phosphodiesterase type 10 (PDE10, Ki = 4 nM). It has >38-fold selectivity for PDE10 over a panel of 60 CNS-associated receptors, enzymes, and ion channels in vitro. Subcutaneous injection of PQ-10 (32 mg/kg) leads to increases in striatal cGMP and phosphorylation of cAMP...
Keywords: 6,7-dimethoxy-4-[(3R)-3-(2-quinoxalinyloxy)-1-pyrrolidinyl]-quinazoline
Application: PDE10 inhibitor
CAS 927691-21-2
MW: 403.4 D
From 59.00€ *
Review