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Item number: TGM-T19723-100mg

Description: AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive reflex responses in the rat. Target: TRP/TRPV Channel. Smiles:...

Keywords:	AMTB
Application:	TRPM8 antagonist
CAS	926023-82-7
MW:	430.99 D

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AMTB

Item number: Cay25336-1

AMTB is an antagonist of transient receptor potential melastatin 8 (TRPM8). It inhibits calcium influx induced by the TRPM8 agonist icilin (Cay-10137) with an IC50 value of 0.58 µM. AMTB (3 mg/kg) decreases the number of volume-induced bladder contractions in a rat model of noxious bladder distension. It also...

Keywords:	N-(3-aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)-benzamide, monohydrochloride
Application:	TRPM8 antagonist
CAS	926023-82-7
MW:	431 D

From 47.00€ *

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