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RRX-001
RRX-001

Item number: TGM-T7400-100mg

Description: RRx-001 is a potent inhibitor ofglucose 6-phosphate dehydrogenase(G6PD) and with potent antimalarial activity. Target: Dehydrogenase, Apoptosis, Parasite. Smiles: [O-][N+](=O)C1(CN(C1)C(=O)CBr)[N+]([O-])=O. References: Zhao H , Ning S , Nolley R , et al. The immunomodulatory anticancer agent, RRx-001,...
Application: Targets NACHT, LRR and PYD domains-containing protein 3 (NLRP3, PYPAF1)
CAS 925206-65-1
MW: 268.02 D
From 48.00€ *
Review
RRx-001
RRx-001

Item number: Cay28846-1

RRx-001 is an anticancer agent. It inhibits growth in a panel of 12 cancer cell lines (IC50s =1.8-6 µM), an effect that is enhanced in SCC VII cells under hypoxic conditions. RRx-001 increases intracellular levels of reactive oxygen species (ROS) in HT-29 and SCC VII cells in a concentration- and time-dependent...
Keywords: ABDNAZ, 2-bromo-1-(3,3-dinitro-1-azetidinyl)-ethanone
Application: Antineoplastic
CAS 925206-65-1
MW: 268 D
From 60.00€ *
Review