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Item number: Cay36229-1

DUBs-IN-2 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 280 nM). It is selective for USP8 over USP7 (IC50 = >100 µM). DUBs-IN-2 increases the level of programmed cell death protein ligand 1 (PD-L1) in H460 cells when used at a concentration of 2 µM and PC-9 cells at 2 and 4 µM. Intraperitoneal...

Keywords:	Deubiquitinase Inhibitor 2, DUBs Inhibitor 2, HY-50737A, 9-(ethoxyimino)-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile
Application:	USP8 inhibitor
CAS	924296-19-5
MW:	275.3 D

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