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DUB-IN-1
Item number: Cay41737-10
DUB-IN-1 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 0.85 µM). It is selective for USP8 over USP7 (IC50 = >100 µM). It inhibits the proliferation of LN-229, U87MG, and T98G glioblastoma cells when used at concentrations ranging from 200 to 800 nM. DUB-IN-1 (500 and 800 nM) reduces the migration...
| Keywords: | Deubiquitinase Inhibitor 1, Deubiquitinase-IN-1, DUB Inhibitor 1, DUBs Inhibitor 1, DUBs-IN-1, 9-[(phenylmethoxy)... |
| Application: | USP8 inhibitor |
| CAS | 924296-18-4 |
| MW: | 337.3 D |
From 132.00€
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DUB-IN-1
Item number: TGM-T11110-100mg
Description: DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific protease (USPs). Target: DUB. Smiles: N#Cc1nc2\C(=N\OCc3ccccc3)c3ccccc3-c2nc1C#N. References: Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues...
| CAS | 924296-18-4 |
| MW: | 337.33 D |
From 96.00€
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