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DUB-IN-3
Item number: Cay41594-10
DUB-IN-3 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 0.56 µM). It is selective for USP8 over USP7 (IC50 = >100 µM). DUB-IN-3 is also an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) papain-like protease (PLpro) when Z-LRGG-AMC is used as a substrate (IC50 = 12.5 µM) but...
| Keywords: | Deubiquitinase Inhibitor 3, Deubiquitinase-IN-3, DUBs Inhibitor 3, DUBs-IN-3, HBX 90397,... |
| Application: | USB8 inhibitor |
| CAS | 924296-17-3 |
| MW: | 287.3 D |
From 431.00€
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DUB-IN-3
Item number: TGM-T11112-100mg
Description: DUB-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor with an IC50 of 0.56 µM for USP8. Target: DUB. Smiles: C=CCO\N=C1/c2ccccc2-c2nc(C#N)c(nc12)C#N. References: Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential...
| CAS | 924296-17-3 |
| MW: | 287.28 D |
From 136.00€
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