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VU534
Item number: TGM-T77594-100mg
Description: VU534 is a NAPE-PLD agonist with an EC50 of 0.30 µM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 µM for sEH.VU534 is used in diseases related to cardiometabolism. Target: Phospholipase, FAAH, Epoxide Hydrolase. Smiles: CC1=CC2=C(SC(NC(=O)C3CCN(CC3)S(=O)(=O)C3=CC=C(F)C=C3)=N2)C(C)=C1....
| Application: | NAPE-PLD activator |
| CAS | 923509-20-0 |
| MW: | 447.55 D |
From 37.00€
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VU534
Item number: Cay39744-10
VU534 is an activator of N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (NAPE-PLD), which hydrolyzes NAPEs into N-acyl ethanolamines (NAEs) and phosphatidic acid. It increases NAPE-PLD activity in cell-free assays (EC50s = 0.3 and 0.93 µM for the recombinant mouse and human enzymes, respectively). VU534...
| Keywords: | N-Acyl-Phosphatidylethanolamine-Hydrolysing Phospholipase D Activator 534, NAPE-PLD Activator 534,... |
| Application: | NAPE-PLD activator |
| CAS | 923509-20-0 |
| MW: | 447.5 D |
From 115.00€
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