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Item number: TGM-T16398-100mg

Description: Opicapone (BIA 9-1067) reduces the ATP content of the cells (IC50: 98 µM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for the research of Parkinson's disease and motor fluctuations. Target: Transferase. Smiles:...

Keywords:	BIA 9-1067
Application:	Targets catechol O-methyltransferase [EC:2.1.1.6] (COMT)
CAS	923287-50-7
MW:	413.17 D

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Opicapone

Item number: Cay34253-10

Opicapone is a peripherally selective inhibitor of catechol-O-methyltransferase (COMT). It inhibits COMT activity in rat liver, but not brain, homogenates (ED50 = 1.05 mg/kg). Opicapone (3 mg/kg) increases plasma levels of L-DOPA (Cay-13248) and reduces plasma levels of 3-O-methyl-DOPA (3-OMD) when administered in...

Keywords:	BIA 9-1067, 5-[3-(2,5-dichloro-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-3-nitro-1,2-benzenediol
Application:	COMT inhibitor
CAS	923287-50-7
MW:	413.2 D

From 35.00€ *

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