2 products were found matching "920509-32-6"!
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Resmetirom
Item number: TGM-T3595-100mg
Description: Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor beta (THR-beta) agonist. Target: Thyroid hormone receptor(THR). Smiles: CC(C)c1cc(Oc2c(Cl)cc(cc2Cl)-n2nc(C#N)c(=O)[nH]c2=O)n[nH]c1=O. References: Kelly, M., Pietranico-Cole, S., Larigan, J., Haynes, N., Reynolds, C., & Scott, N. et al....
| Keywords: | MGL3196, VIA-3196 |
| Application: | Targets thyroid hormone receptor beta (THRB, NR1A2) |
| CAS | 920509-32-6 |
| MW: | 435.22 D |
From 33.00€
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MGL-3196
Item number: Cay23845-1
MGL-3196 is an agonist of thyroid hormone receptor beta (TRbeta, EC50s = 0.21 and 3.74 µM for TRbeta and TRalpha, respectively). It also inhibits ether-a-go-go-related gene (ERG) potassium channels (IC50 = 30 µM). MGL-3196 is a liver-directed compound, with a liver to plasma ratio of 8:1 in mice with diet-induced...
| Keywords: | 2-[3,5-dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro-3,5-dioxo-1,2,4-triaz... |
| Application: | Thyroid hormone receptor beta agonist |
| CAS | 920509-32-6 |
| MW: | 435.2 D |
From 38.00€
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