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Zatebradine hydrochloride
Item number: TGM-T13387L-100mg
Description: Zatebradine hydrochloride (UL-FS-49CL) is a highly effective and effective HCN Channel inhibitor (IC50:1.96 µM). HCN Channel is an effective hyperpolarization activated loop nucleotide gated channel. Zatebradine hydrochloride blocks slow inward currents through human HCN1, HCN2, HCN3, and HCN4 channels...
| Keywords: | UL-FS-49CL, UL-FS-49 |
| Application: | HCN channel blocker |
| CAS | 91940-87-3 |
| MW: | 493.04 D |
From 45.00€
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Zatebradine (hydrochloride)
Item number: Cay18608-25
Zatebradine is a bradycardic compound that blocks hyperpolarization-activated inward current (If) through cyclic nucleotide-gated cation (HCN) channels in sinoatrial node cells (IC50s = 1.83, 2.21, 1.9, and 1.88 µM, respectively for HCN1-4 in vitro). Additionally, it can block voltage-gated outward K+ (IK) currents...
| Keywords: | UL-FS 49, 3-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one,... |
| Application: | HCN channel blocker |
| CAS | 91940-87-3 |
| MW: | 493 D |
From 145.00€
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