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Avoralstat
Item number: TGM-T14358-100mg
Description: Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema. Target: Others. Smiles: COc1cc(c(cc1C=C)C(=O)Nc1ccc(cc1)C(N)=N)-c1ccc(nc1C(O)=O)C(=O)NCC1CC1. References: Aygoren-Pursun E, et al. Prophylaxis of hereditary angioedema attacks: A...
| Keywords: | BCX4161 |
| Application: | Kallikrein / TMPRSS2 inhibitor |
| CAS | 918407-35-9 |
| MW: | 513.54 D |
From 48.00€
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Avoralstat
Item number: Cay35610-5
Avoralstat is an inhibitor of kallikrein, a serine protease involved in the contact activation system. It inhibits kallikrein activity in isolated human plasma (EC50s = 1.14-11.1 nM). Avoralstat also inhibits transmembrane serine protease 2 (TMPRSS2, IC50 = 2.73 nM), a serine protease required for entry of severe...
| Keywords: | BCX 4161,... |
| Application: | Kallikrein / TMPRSS2 inhibitor |
| CAS | 918407-35-9 |
| MW: | 513.6 D |
From 46.00€
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