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BMS-779788
BMS-779788

Item number: TGM-T3970-100mg

Description: BMS-779788 (XL-652) is an LXRalpha/beta partial agonist (IC50: 68/14 nM). Target: Liver X Receptor. Smiles: CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O. References: Kick, E., Martin, R., Xie, Y., Flatt, B., Schweiger, E., & Wang, T. et al. (2015). Liver X Receptor (LXR) partial...
Keywords: XL-652, BMS-788, XL652, XL 652, EXEL04286652
Application: LXR alpha & beta partial agonist
CAS 918348-67-1
MW: 509.06 D
From 33.00€ *
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BMS 779788
BMS 779788

Item number: Cay27339-1

BMS 779788 is a partial agonist of liver X receptor alpha (LXRalpha) and LXRbeta (Kis = 68 and 14 nM, respectively, in a radioligand binding assay). It activates LXRalpha and LXRbeta with EC50 values of 230 and 250 nM, respectively, in a transactivation assay. BMS 779788 increases expression of ATP-binding cassette...
Keywords: 2-[1-(2-chlorophenyl)-1-methylethyl]-alpha,alpha-dimethyl-1-[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]-1H-imidazole-4-methanol
Application: LXR alpha & beta partial agonist
CAS 918348-67-1
MW: 509.1 D
From 78.00€ *
Review