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Item number: TGM-T11387-1mg

Description: Gemfibrozil 1-O-beta-Glucuronide, a metabolite of Gemfibrozil, is a potent and competitive inhibitor of P450 (CYP) isoform CYP2C8, with an IC50 of 4.07 µM. Target: Others. Smiles: Cc1ccc(C)c(OCCCC(C)(C)C(=O)O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)c1. References: Shitara Y, et al. Gemfibrozil and...

CAS	91683-38-4
MW:	426.46 D

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Gemfibrozil 1-O-beta-Glucuronide

Item number: Cay19080-1

Gemfibrozil 1-O-beta-glucuronide is a major metabolite of gemfibrozil (Cay-14835) that is formed when gemfibrozil undergoes glucuronidation by UDP-glucuronosyltransferase (UGT) 2B7. Gemfibrozil 1-O-beta-glucuronide is an inhibitor of the cytochrome P450 (CYP) isoform CYP2C8 (IC50 = 4.1 µM). It is taken up by organic...

Keywords:	1-[5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate], beta-D-glucopyranuronic acid
Application:	Gemfibrozil metabolite
CAS	91683-38-4
MW:	426.5 D

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