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SP-420
Item number: TGM-T5344-100mg
Description: SP-420 is a novel orally active iron chelator. Target: Others. Smiles: OC1=C(C=CC(OCCOCCOC)=C1)C2=N[C@](C(O)=O)(C)CS2. References: Bergeron RJ, et al. Substituent effects on desferrithiocin and desferrithiocin analogue iron-clearing and toxicity profiles. J Med Chem. 2012 Aug 23,55(16):7090-103.
| Keywords: | SP 420 |
| CAS | 911714-45-9 |
| MW: | 355.41 D |
From 31.00€
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SP-420
Item number: Cay28498-1
SP-420 is an iron chelator and a derivative of desferrothiocin. It induces iron excretion in rat bile and urine with an iron-clearing efficiency (ICE) value of 26.7% when administered at a dose of 300 µmol/kg and decreases iron levels in rat liver and heart at 384 µmol/kg per day. SP-420 (75 µmol/kg) also induces...
| Keywords: | (S)-4'-(HO)-DADFT-norPE, (4S)-4,5-dihydro-2-[2-hydroxy-4-[2-(2-methoxyethoxy)ethoxy]phenyl]-4-methyl-4-thiazolecarboxylic... |
| Application: | Iron chelator |
| CAS | 911714-45-9 |
| MW: | 355.4 D |
From 44.00€
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