2 products were found matching "909725-62-8"!
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W146 (trifluoroacetate salt)
Item number: CAY10009109-1
W146 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (Ki = 77 nM). It is selective for S1P1 over S1P2, S1P3, and S1P5 receptors (Kis = >10 µM for all). W146 prevents ligand-induced receptor internalization in CHO cells and inhibits the phosphorylation of ERK1 and Akt when used at a concentration of 10 µM....
| Keywords: | [3R-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid, mono(trifluoroacetate) |
| Application: | S1P1 receptor antagonist |
| CAS | 909725-62-8 |
| MW: | 456.4 D |
From 107.00€
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W146 TFA
Item number: TGM-T41237-10mg
Description: W146 TFA is a selective antagonist of the sphingosine-1-phosphate receptor 1 (S1PR1), exhibiting an EC50 value of 398 nM. Target: Others. Smiles: OC(=O)C(F)(F)F.CCCCCCc1cccc(NC(=O)[C@H](N)CCP(O)(O)=O)c1
| Application: | S1P1 receptor antagonist |
| CAS | 909725-62-8 |
| MW: | 456.399 D |
From 194.00€
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