3 products were found matching "905586-69-8"!
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AZ960
Item number: TGM-T6309-10mg
Description: AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM). Target: Parasite, Apoptosis, Virus Protease, JAK. Smiles: C[C@H](Nc1nc(Nc2cc(C)[nH]n2)c(F)cc1C#N)c1ccc(F)cc1. References: Gozgit JM, et al. J Biol Chem. 2008, 283(47), 32334-32343.
| Keywords: | AZ 960 |
| Application: | JAK2 inhibitor |
| CAS | 905586-69-8 |
| MW: | 354.36 D |
From 66.00€
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AZ 960
Item number: Cay16731-1
Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. Many myeloproliferative diseases have been linked to a mutation in JAK2 where a switch from valine to phenylalanine occurs at the 617 position (V617F)....
| Keywords: | 5-fluoro-2-[[(1S)-1-(4-fluorophenyl)ethyl]amino]-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3-pyridinecarbonitrile |
| Application: | JAK2 inhibitor |
| CAS | 905586-69-8 |
| MW: | 354.4 D |
From 158.00€
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AZ 960
Item number: AG-CR1-3752-M001
AZ-960 is a potent, selective and ATP-competitive JAK2 inhibitor that inhibits JAK2 kinase with a Ki of 0.45nM in vitro (3-fold selective over JAK3) and induces growth arrest and apoptosis in adult T cell leukemia (ATL) cells. Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for...
| Keywords: | AZ960, AZ-960 |
| Application: | JAK2 inhibitor |
| CAS | 905586-69-8 |
| MW: | 354.4 D |
From 77.00€
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